The CCAAT box is one of the most common cis-elements present in eukaryotic promoters
and is bound by the transcription factor NUCLEAR FACTOR Y (NF-Y). NF-Y is composed of …

… Using NIH3T3 cells expressing full-length Ras-GRF in immunoprecipitation assays, we
showed that commercially available anti-C-terminal and our anti-N-terminal antiserum …

… ) (rmsd of 0.73 Å over 164 Cα pairs), with some notable differences (Figure 2A): (1) NF-YB
and NF-YC N termini are structurally better defined in the DNA complex; (2) the bidentate salt …

For many plant species, reproductive success relies on the proper timing of flowering, and
photoperiod provides a key environmental input. Photoperiod-dependent flowering depends …

The serine/threonine kinase PAK4 was identified first as an effector molecule for the Rho
GTPase Cdc42. PAK4 differs from other members of the PAK family both in sequence and …

… However, the CCT domain N-terminal portion is not perfectly superimposable with the NF-YA
A1 helix involved in the interactions with the HFD dimer, yet it does share its highly basic …

Normal cell growth requires a precisely controlled balance between cell death and survival.
This involves activation of different types of intracellular signaling cascades within the cell. …

Photoperiod dependent flowering is one of several mechanisms used by plants to initiate
the developmental transition from vegetative growth to reproductive growth. The NUCLEAR …

Rice flowering is controlled by changes in the photoperiod that promote the transition to the
reproductive phase as days become shorter. Natural genetic variation for flowering time has …

Background NF-Y is a transcription factor that recognizes with high specificity and affinity the
widespread CCAAT box promoter element. It is formed by three subunits: NF-YA and the NF…