User profiles for N. Chia

Nicholas Chia

- Verified email at anl.gov - Cited by 8768

CHIA NA YU

- Verified email at duke-nus.edu.sg - Cited by 2194

The microbiome of the chicken gastrointestinal tract

CJ Yeoman, N Chia, P Jeraldo, M Sipos… - Animal health …, 2012 - cambridge.org
The modern molecular biology movement was developed in the 1960s with the conglomeration
of biology, chemistry, and physics. Today, molecular biology is an integral part of studies …

[HTML][HTML] Molecular classification of gastric cancer

NY Chia, P Tan - Annals of Oncology, 2016 - Elsevier
Gastric cancer (GC), a heterogeneous disease characterized by epidemiologic and
histopathologic differences across countries, is a leading cause of cancer-related death. Treatment …

The genetics of psoriasis 2001: the odyssey continues

…, T Henseler, S Jenisch, P Stuart, N Chia… - Archives of …, 2001 - jamanetwork.com
… D and D′ indicate 2 genetically different disease alleles at a particular locus;N, any normal
allele at that locus. Circles indicate female members; squares, male members; and solid …

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

…, M DeFelice, R Barry, W Brodeur, J Camarata, N Chia… - Science, 2007 - science.org
New strategies for prevention and treatment of type 2 diabetes (T2D) require improved insight
into disease etiology. We analyzed 386,731 common single-nucleotide polymorphisms (…

[HTML][HTML] Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls

J Chen, N Chia, KR Kalari, JZ Yao, M Novotna… - Scientific reports, 2016 - nature.com
… the fecal microbiota in relapsing remitting MS (RRMS) (n = 31) patients to that of age- and
gender-matched healthy controls (n = 36). Phylotype profiles of the gut microbial populations …

Transposable elements have rewired the core regulatory network of human embryonic stem cells

G Kunarso, NY Chia, J Jeyakani, C Hwang, X Lu… - Nature …, 2010 - nature.com
Detection of new genomic control elements is critical in understanding transcriptional regulatory
networks in their entirety. We studied the genome-wide binding locations of three key …

A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity

NY Chia, YS Chan, B Feng, X Lu, YL Orlov, D Moreau… - Nature, 2010 - nature.com
… NFRKB (N) enhanced reprogramming by twofold whereas YAP1 did not show a positive
effect on reprogramming. Furthermore, knockdown of PRDM14 or NFRKB affected the …

[PDF][PDF] Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene

…, PE Stuart, I Nistor, R Hiremagalore, NVC Chia… - The American Journal of …, 2006 - cell.com
Previous studies have narrowed the interval containing PSORS1, the psoriasis-susceptibility
locus in the major histocompatibility complex (MHC), to an ∼300-kb region containing HLA-…

[HTML][HTML] Single-cell RNA sequencing shows the immunosuppressive landscape and tumor heterogeneity of HBV-associated hepatocellular carcinoma

…, ACY Chan, ETY Cheung, DTW Yau, NH Chia… - Nature …, 2021 - nature.com
… Consistently, with immunohistochemistry (IHC) on a cohort of HCC (n = 29), we also
detected a statistically significant association between LAIR1 and CD163 expression in HCC (…

[HTML][HTML] Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition

…, N Goldenfeld, JA Woods, BA White, N Chia… - Molecular …, 2014 - Springer
… To prepare the reads for this step, we took reads from the previous step just before the
stitching procedure, remove the gaps and then stitched them with a pad sequence of “N” bases. …