The seasonal peculiarities of force–frequency relationships in active ground squirrel Spermophilus undulatus ventricle

OV Nakipova, NM Zakharova, LA Andreeva… - Cryobiology, 2007 - Elsevier
The plasticity of calcium homeostasis is of crucial importance for the unique ability of the
hibernators’ heart to function under conditions of body temperature changing from 37C to near …

[HTML][HTML] Transport of Ca2+ and Ca2+-Dependent Permeability Transition in the Liver and Heart Mitochondria of Rats with Different Tolerance to Acute Hypoxia

…, EY Talanov, VS Starinets, KS Tenkov, NM Zakharova… - Biomolecules, 2020 - mdpi.com
… The Ca 2+ concentration in the incubation medium was monitored spectrophotometrically
with an arsenazo III indicator at 675–685 nm using a plate reader Tecan Spark 10M (Tecan, …

Antipsychotic inductors of brain hypothermia and torpor-like states: perspectives of application

…, NP Komelina, MO Khrenov, NM Zakharova - …, 2017 - Springer
Hypothermia and hypometabolism (hypometabothermia) normally observed during natural
hibernation and torpor, allow animals to protect their body and brain against the damaging …

[HTML][HTML] Thymulin, free or bound to PBCA nanoparticles, protects mice against chronic septic inflammation

…, MO Khrenov, SB Parfenyuk, NM Zakharova… - Plos one, 2018 - journals.plos.org
In the present work, we aimed to study the effects of free and polybutylcyanoacrylate
nanoparticle-bound thymulin on immune cell activity in mice with chronic inflammation. NF-κB, …

A pharmacological composition for induction of a reversible torpor-like state and hypothermia in rats

NM Zakharova, YS Tarahovsky, IS Fadeeva… - Life sciences, 2019 - Elsevier
… The optical density was measured at 450 nm with a Titertek Multiscan MCC/340 plate …
contains spherical drops of soy oil, of about 300 nm in diameter, stabilized with soy lecithin as an …

Cloning and detailed mapping of the fra-ymt region of the Yersinia pestis pFra plasmid

…, GA Karimova, NM Zakharova… - Molekuliarnaia …, 1991 - europepmc.org
The genetical libraries of the pFra plasmid of Yersinia pestis genes were obtained by
insertion into the PstI, SalGI, EcoRI, XhoI restriction sites of the cosmid vector pHC79. The …

Morphological marker of tumor progression in laryngeal cancer

SN Shatokhina, NM Zakharova, MG Dedova… - Voprosy …, 2013 - europepmc.org
Dynamic observation of 32 patients with laryngeal cancer, treated with radiotherapy and
combination therapy, was performed using diagnostic technology" Litos-system", including the …

Seasonal features of the effects of blockade of opioid receptors on adaptive behavior in hibernating animals

TP Semenova, NM Zakharova - Neuroscience and Behavioral Physiology, 2015 - Springer
Studies of hibernating Yakutianian long-tailed ground squirrels (n = 42) addressed the
effects of blockade of opioid receptors with naloxone on behavior in an open field and a …

Effect of Cooling on Force-Frequency Relationship, Rest Potentiation, and Frequency-Dependent Acceleration of Relaxation in the Guinea Pig Myocardium

AS Averin, NM Zakharova, SV Tarlachkov - Journal of Evolutionary …, 2021 - Springer
While deep hypothermia is well known to lead to cardiac malfunction up to circulatory arrest,
mild hypothermia can prevent hypoxic damage to the heart. Importantly, a large body of …

Long-term pharmacological torpor of rats with feedback-controlled drug administration

NM Zakharova, YS Tarahovsky, NP Komelina… - Life Sciences in Space …, 2021 - Elsevier
Zakharova: The research peresented in the article was supported by Russian Foundation
for Advanced Research. Dr. Zakharova is one of the inventors according to the patent RU 2 …