User profiles for N. J. Cox

Nancy Cox

Vanderbilt University Medical Center
Verified email at vanderbilt.edu
Cited by 88972

Finding the missing heritability of complex diseases

TA Manolio, FS Collins, NJ Cox, DB Goldstein… - Nature, 2009 - nature.com
Genome-wide association studies have identified hundreds of genetic variants associated
with complex human diseases and traits, and have provided valuable insights into their …

[HTML][HTML] Guidelines for investigating causality of sequence variants in human disease

…, LG Biesecker, DF Conrad, GM Cooper, NJ Cox… - Nature, 2014 - nature.com
The discovery of rare genetic variants is accelerating, and clear guidelines for distinguishing
disease-causing sequence variants from the many potentially functional variants present in …

Global epidemiology of influenza: past and present

NJ Cox, K Subbarao - Annual review of medicine, 2000 - annualreviews.org
… A historic exception occurred on a military base in New Jersey in 1976, when a limited
influenza outbreak was caused by a swine influenza A virus that was transmitted from person to …

[HTML][HTML] The genotype-tissue expression (GTEx) project

…, Y Marcus, M Basile, J Liu, J Zhu, Z Tu, NJ Cox… - Nature …, 2013 - nature.com
Genome-wide association studies have identified thousands of loci for common diseases,
but, for the majority of these, the mechanisms underlying disease susceptibility remain …

The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans

…, HK Im, A Konkashbaev, DL Nicolae, NJ Cox… - Science, 2015 - science.org
Understanding the functional consequences of genetic variation, and how it affects complex
human disease and quantitative traits, remains a critical challenge for biomedicine. We …

Antigenic and genetic characteristics of swine-origin 2009 A (H1N1) influenza viruses circulating in humans

…, DB Jernigan, TM Uyeki, DJ Smith, AI Klimov, NJ Cox - science, 2009 - science.org
Since its identification in April 2009, an A(H1N1) virus containing a unique combination of
gene segments from both North American and Eurasian swine lineages has continued to …

Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP)

SA Harper, K Fukuda, TM Uyeki, NJ Cox… - Morbidity and Mortality …, 2005 - JSTOR
This report updates the 2004 recommendations by the Advisory Committee on
Immunization Practices (ACIP) regarding the use of influenza vaccine and antiviral agents (CDC. …

Influenza-associated hospitalizations in the United States

…, E Weintraub, L Brammer, CB Bridges, NJ Cox… - Jama, 2004 - jamanetwork.com
ContextRespiratory viral infections are responsible for a large number of hospitalizations in
the United States each year.ObjectiveTo estimate annual influenza-associated …

Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3)

…, RD Cox, GM Lathrop, VV Boriraj, X Chen, NJ Cox… - Nature, 1996 - nature.com
THE disease non-insulin-dependent (type 2) diabetes mellitus (NIDDM) is characterized by
abnormally high blood glucose resulting from a relative deficiency of insulin 1 . It affects …

Obesity-associated variants within FTO form long-range functional connections with IRX3

…, RD Acemel, M Manzanares, A Nagy, NJ Cox… - Nature, 2014 - nature.com
Genome-wide association studies (GWAS) have reproducibly associated variants within
introns of FTO with increased risk for obesity and type 2 diabetes (T2D) 1 , 2 , 3 . Although the …