User profiles for N. C. Wu

Nicholas C. Wu

University of Illinois at Urbana-Champaign
Verified email at illinois.edu
Cited by 10581

[HTML][HTML] Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies

M Yuan, H Liu, NC Wu, IA Wilson - Biochemical and biophysical research …, 2021 - Elsevier
Immediately from the outset of the COVID-19 pandemic, researchers from diverse
biomedical and biological disciplines have united to study the novel pandemic virus, SARS-CoV-2. …

A perspective on the structural and functional constraints for immune evasion: insights from influenza virus

NC Wu, IA Wilson - Journal of molecular biology, 2017 - Elsevier
Influenza virus evolves rapidly to constantly escape from natural immunity. Most humoral
immune responses to influenza virus target the hemagglutinin (HA) glycoprotein, which is the …

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

…, J Ricketts, MJ Ricciardi, SA Rawlings, NC Wu… - Science, 2020 - science.org
Countermeasures to prevent and treat coronavirus disease 2019 (COVID-19) are a global
health priority. We enrolled a cohort of severe acute respiratory syndrome coronavirus 2 (…

A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV

M Yuan, NC Wu, X Zhu, CCD Lee, RTY So, H Lv… - Science, 2020 - science.org
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome–coronavirus 2 (SARS-CoV-2) has now become a pandemic, but there is currently …

Influenza hemagglutinin structures and antibody recognition

NC Wu, IA Wilson - Cold Spring Harbor …, 2020 - perspectivesinmedicine.cshlp.org
Hemagglutinin (HA) is most abundant glycoprotein on the influenza virus surface. Influenza
HA promotes viral entry by engaging the receptor and mediating virus–host membrane fusion…

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

M Yuan, D Huang, CCD Lee, NC Wu, AM Jackson… - Science, 2021 - science.org
NC, not categorized in the original studies; NS, no structure available. (D) Neutralization of
pseudotyped SARS-CoV-2 virus and variants carrying K417N or E484K mutations. We tested …

Challenges to global RFID adoption

NC Wu, MA Nystrom, TR Lin, HC Yu - Technovation, 2006 - Elsevier
… Nien-Chu Wu received his BS degree in aeronautical engineering and his MS in mechanical
engineering from Feng-Chia University, Taichung, Taiwan in 1985 and 1991, respectively. …

[HTML][HTML] Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020

…, OTY Tsang, H Lv, RLW Ko, NC Wu… - …, 2020 - eurosurveillance.org
Background The ongoing coronavirus disease (COVID-19) pandemic has major impacts on
health systems, the economy and society. Assessing infection attack rates in the population …

Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape

…, IA Wilson, M Geyer, KU Ludwig, BM Hällberg, NC Wu… - Science, 2021 - science.org
INTRODUCTION The global scale and rapid spread of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) pose unprecedented challenges to society, health care systems, …

Structural basis of a shared antibody response to SARS-CoV-2

M Yuan, H Liu, NC Wu, CCD Lee, X Zhu, F Zhao… - Science, 2020 - science.org
Molecular understanding of neutralizing antibody responses to severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) could accelerate vaccine design and drug discovery. …