[PDF][PDF] Sensing of bacterial cyclic dinucleotides by the oxidoreductase RECON promotes NF-κB activation and shapes a proinflammatory antibacterial state

AP McFarland, S Luo, F Ahmed-Qadri, M Zuck… - Immunity, 2017 - cell.com
Bacterial and host cyclic dinucleotides (cdNs) mediate cytosolic immune responses through
the STING signaling pathway, although evidence suggests that alternative pathways exist. …

[HTML][HTML] The promise of systems biology approaches for revealing host pathogen interactions in malaria

M Zuck, LS Austin, SA Danziger, JD Aitchison… - Frontiers in …, 2017 - frontiersin.org
Despite global eradication efforts over the past century, malaria remains a devastating
public health burden, causing almost half a million deaths annually (WHO, 2016 ). A detailed …

[HTML][HTML] Liver stage malaria infection is controlled by host regulators of lipid peroxidation

…, N Arang, AN Douglass, CL Fortin, M Zuck… - Cell Death & …, 2020 - nature.com
The facets of host control during Plasmodium liver infection remain largely unknown. We
find that the SLC7a11-GPX4 pathway, which has been associated with the production of …

Extrusions are phagocytosed and promote Chlamydia survival within macrophages

M Zuck, T Ellis, A Venida, K Hybiske - Cellular microbiology, 2017 - Wiley Online Library
… PS rings surrounding the extrusion membrane (Figure 2m). Because PS is typically found on
the … About 24.4% of extrusions exhibited no surface PS (Figure 2m). Little PS exposure was …

A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor

C Yokota, M Kofron, M Zuck, DW Houston, H Isaacs… - 2003 - journals.biologists.com
Convergent extension behaviour is critical for the formation of the vertebrate body axis. In
Xenopus, components of the Wnt signaling pathway have been shown to be required for …

[HTML][HTML] Actin Recruitment to the Chlamydia Inclusion Is Spatiotemporally Regulated by a Mechanism That Requires Host and Bacterial Factors

E Chin, K Kirker, M Zuck, G James, K Hybiske - 2012 - journals.plos.org
The ability to exit host cells at the end of their developmental growth is a critical step for the
intracellular bacterium Chlamydia. One exit strategy, extrusion, is mediated by host signaling …

Genetic Organization of the hrp Gene Cluster and dspAE/BF Operon in Erwinia herbicola pv. gypsophilae

H Mor, S Manulis, M Zuck, R Nizan… - Molecular plant …, 2001 - Am Phytopath Society
Erwinia herbicola pv. gypsophilae induces gall formation in gypsophila that is dependent on
the existence of a pathogenicity plasmid (pPATH Ehg ). We previously demonstrated the …

[PDF][PDF] Antibody interference by a non-neutralizing antibody abrogates humoral protection against Plasmodium yoelii liver stage

…, O Trakhimets, SL Brown, A Watson, M Zuck… - Cell reports, 2021 - cell.com
… À9 M in a 1:1 binding model, consisting of a fast kon (9.804x10 … À7 M (Figure 2A) and with
an association and dissociation kinetics values of kon (9.804 3 104 1/Ms) and koff (À1.179 3 …

Conservation of extrusion as an exit mechanism for Chlamydia

M Zuck, A Sherrid, R Suchland, T Ellis… - FEMS Pathogens and …, 2016 - academic.oup.com
Chlamydiae exit via membrane-encased extrusion or through lysis of the host cell. Extrusions
are novel, pathogen-containing structures that confer infectious advantages to Chlamydia, …

Induced Production of N-Formyl Alkaloids from Aspergillus fumigatus by Co-culture with Streptomyces peucetius

KM Zuck, S Shipley, DJ Newman - Journal of natural products, 2011 - ACS Publications
Co-culture of the fungus Aspergillus fumigatus with the bacteria Streptomyces peucetius led
to the induction of production of formyl xanthocillin analogues. This mixed fermentation …