[HTML][HTML] MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data
Single-cell transcriptomics reveals gene expression heterogeneity but suffers from stochastic
dropout and characteristic bimodal expression distributions in which expression is either …
dropout and characteristic bimodal expression distributions in which expression is either …
Epstein‐Barr virus strain variation and cancer
Epstein‐Barr virus ( EBV ) is a human tumor virus and is etiologically linked to various
malignancies. Certain EBV ‐associated diseases, such as Burkitt lymphomas and …
malignancies. Certain EBV ‐associated diseases, such as Burkitt lymphomas and …
Why we (usually) don't have to worry about multiple comparisons
… Here we would want to be thinking about “Type M” (magnitude) errors: saying that a … In that
setting, underpowered studies present a real problem because type M errors are more likely …
setting, underpowered studies present a real problem because type M errors are more likely …
Subunit structure of islet-activating protein, pertussis toxin, in conformity with the AB model
M Tamura, K Nogimori, S Murai, M Yajima, K Ito… - Biochemistry, 1982 - ACS Publications
… figure 2: CM-Sepharose chromatography of IAP partially dissociated in 5 M urea. IAP (18
mg) was dissolved in 3 mL of 0.05 M phosphate buffer (pH 6.0) containing 5 M urea and stored …
mg) was dissolved in 3 mL of 0.05 M phosphate buffer (pH 6.0) containing 5 M urea and stored …
Multiple imputation with diagnostics (mi) in R: Opening windows into the black box
Our mi package in R has several features that allow the user to get inside the imputation
process and evaluate the reasonableness of the resulting models and imputations. These …
process and evaluate the reasonableness of the resulting models and imputations. These …
Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice
10.7554/eLife.16351.001 The FDA approved drug rapamycin increases lifespan in rodents
and delays age-related dysfunction in rodents and humans. Nevertheless, important …
and delays age-related dysfunction in rodents and humans. Nevertheless, important …
Clinical manifestations of Takayasu arteritis in India and Japan—new classification of angiographic findings
R Moriwaki, M Noda, M Yajima, BK Sharma… - …, 1997 - journals.sagepub.com
In this retrospective review 102 Indian and 80 Japanese patients with Takayasu arteritis were
compared in regard to their clinical manifestations and angiographic findings. Regardless …
compared in regard to their clinical manifestations and angiographic findings. Regardless …
Suppression of STING associated with LKB1 loss in KRAS-driven lung cancer
…, PT Kirschmeier, CP Paweletz, H Watanabe, M Yajima… - Cancer discovery, 2019 - AACR
Oncogenic KRAS -mutant lung cancers remain treatment-refractory and are resistant to ICB
in the setting of LKB1 loss. These results begin to uncover the key underlying mechanism …
in the setting of LKB1 loss. These results begin to uncover the key underlying mechanism …
Multiple nutritional requirements of lactobacilli: genetic lesions affecting amino acid biosynthetic pathways
T Morishita, Y Deguchi, M Yajima, T Sakurai… - Journal of …, 1981 - Am Soc Microbiol
Genetic lesions responsible for amino acid requirements in several species of multiple
auxotrophic lactobacilli were investigated. Systematic attempts were made to isolate mutants that …
auxotrophic lactobacilli were investigated. Systematic attempts were made to isolate mutants that …
Bifidobacterium bifidum improves intestinal integrity in a rat model of necrotizing enterocolitis
…, MD Halpern, T Kinouchi, M Yajima… - American Journal …, 2009 - journals.physiology.org
Neonatal necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in
premature infants. Oral administration of probiotics has been suggested as a promising strategy …
premature infants. Oral administration of probiotics has been suggested as a promising strategy …