], Nigel Crawford and colleagues reported on the discovery of a distinct nitric oxide synthase
(AtNOS1) in Arabidopsis thaliana that regulates growth and hormonal signaling in plants. …

Alignment algorithms to compare DNA or amino acid sequences are widely used tools in
molecular biology. The algorithms depend on the setting of various parameters, most notably …

… Vingron and Argos [24] studied regions in the optimal alignment that are shared by all …
Vingron and Argos use suboptimal points based on global alignments calculated under an affine …

Regulatory regions of plant genes tend to be more compact than those of animal genes, but
the complement of transcription factors encoded in plant genomes is as large or larger than …

We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest
human cancers. In nearly all the tumours analysed we found bi-allelic inactivation of TP53 …

Microarray analysis has become a widely used tool for the generation of gene expression data
on a genomic scale. Although many significant results have been derived from microarray …

The functional complexity of the human transcriptome is not yet fully elucidated. We report a
high-throughput sequence of the human transcriptome from a human embryonic kidney and …

Motivation: High-throughput sequencing has made the analysis of new model organisms
more affordable. Although assembling a new genome can still be costly and difficult, it is …

TREE-PUZZLE is a program package for quartet-based maximum-likelihood phylogenetic
analysis (formerly PUZZLE, Strimmer and von Haeseler, Mol. Biol. Evol. , 13, 964–969, 1996) …

We introduce a statistical model for microarray gene expression data that comprises data
calibration, the quantification of differential expression, and the quantification of measurement …