User profiles for M. Sze

Marc Sze

Merck Research Laboratories
Verified email at merck.com
Cited by 2492

Diagnosis, management, and prognosis of preschool wheeze

FM Ducharme, MT Sze, B Chauhan - The Lancet, 2014 - thelancet.com
Preschool children (ie, those aged 5 years or younger) with wheeze consume a disproportionately
high amount of health-care resources compared with older children and adults with …

Bacterial microbiome of lungs in COPD

MA Sze, JC Hogg, DD Sin - International journal of chronic …, 2014 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is currently the third leading cause of death
in the world. Although smoking is the main risk factor for this disease, only a minority of …

Impact of coronavirus disease 2019 (COVID-19) outbreak on ST-segment–elevation myocardial infarction care in Hong Kong, China

…, S Lam, A Wong, A Yung, M Sze… - … Quality and Outcomes, 2020 - Am Heart Assoc
The extent to which a community outbreak of infection like COVID-19 stresses other parts of
healthcare system like STEMI care is largely unknown. Contemporary COVID-19 infection …

The lung tissue microbiome in chronic obstructive pulmonary disease

MA Sze, PA Dimitriu, S Hayashi, WM Elliott… - American journal of …, 2012 - atsjournals.org
… Also, unequal and inadequate sample size may be an issue. In the former, samples from
five moderate patients with COPD were compared with eight control samples. In the latter, BAL …

Looking for a signal in the noise: revisiting obesity and the microbiome

MA Sze, PD Schloss - MBio, 2016 - Am Soc Microbiol
… results across studies to increase the effective sample size. It is possible that there were small
… We also calculated the actual sample size needed on the basis of the effect size of each …

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

…, P Jacques, J Maelfait, E Verheugen, M Kool, M Sze… - Nature …, 2011 - nature.com
size tube set to 70 kV and 145 μA and the magnification at 1.3 (field of view = 91.08 mm).
A general purpose reconstruction mode was used in a 512 × 512 matrix of 150-μm pixel size. …

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis

…, L Duprez, SB Berger, T Divert, A Gonçalves, M Sze… - Nature, 2014 - nature.com
… Sample size estimation was done by using G power statistics. There was no randomization
but stratification was used to achieve a similar sex ratio among experimental groups. No …

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis

L Vereecke, M Sze, CM Guire, B Rogiers… - Journal of Experimental …, 2010 - rupress.org
A20 is a nuclear factor κB (NF-κB) target gene that encodes a ubiquitin-editing enzyme that
is essential for the termination of NF-κB activation after tumor necrosis factor (TNF) or …

Past, present, and future research on the lung microbiome in inflammatory airway disease

LJ Caverly, YJ Huang, MA Sze - Chest, 2019 - Elsevier
COPD, asthma, and cystic fibrosis (CF) are obstructive lung diseases with distinct
pathophysiologies and clinical phenotypes. In this paper, we highlight recent advances in our …

Host response to the lung microbiome in chronic obstructive pulmonary disease

MA Sze, PA Dimitriu, M Suzuki… - American journal of …, 2015 - atsjournals.org
Rationale: The relatively sparse but diverse microbiome in human lungs may become less
diverse in chronic obstructive pulmonary disease (COPD). This article examines the …