User profiles for M. Shurtleff

Matthew Shurtleff

Scientist at Lycia Therapeutics
Verified email at lyciatx.com
Cited by 1909

[BOOK][B] Diagnosing plant diseases caused by nematodes.

MC Shurtleff, CW Averre - 2000 - cabdirect.org
This book helps to simply the diagnosis of nematode problems and identify plant parasitic
nematodes (PPN). Chapter 1 gives a general description of physical characteristics of PPN …

Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction

MJ Shurtleff, MM Temoche-Diaz, KV Karfilis, S Ri… - elife, 2016 - elifesciences.org
10.7554/eLife.19276.001 Exosomes are small vesicles that are secreted from metazoan cells
and may convey selected membrane proteins and small RNAs to target cells for the control …

Extracellular vesicles and cancer: caveat lector

MJ Shurtleff, MM Temoche-Diaz… - Annual Review of …, 2018 - annualreviews.org
A great deal of interest has developed around evidence of a role for or a marker of extracellular
vesicles (EVs)/exosomes and metastatic cancer. However, the strength of a functional …

Broad role for YBX1 in defining the small noncoding RNA composition of exosomes

MJ Shurtleff, J Yao, Y Qin… - Proceedings of the …, 2017 - National Acad Sciences
RNA is secreted from cells enclosed within extracellular vesicles (EVs). Defining the RNA
composition of EVs is challenging due to their coisolation with contaminants, lack of …

RNA trafficking by acute myelogenous leukemia exosomes

J Huan, NI Hornick, MJ Shurtleff, AM Skinner… - Cancer research, 2013 - AACR
Extrinsic signaling cues in the microenvironment of acute myelogenous leukemia (AML)
contribute to disease progression and therapy resistance. Yet, it remains unknown how the …

Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes

MM Temoche-Diaz, MJ Shurtleff, RM Nottingham… - Elife, 2019 - elifesciences.org
10.7554/eLife.47544.001 Extracellular vesicles (EVs) encompass a variety of vesicles secreted
into the extracellular space. EVs have been implicated in promoting tumor metastasis, …

The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins

MJ Shurtleff, DN Itzhak, JA Hussmann… - Elife, 2018 - elifesciences.org
10.7554/eLife.37018.001 The endoplasmic reticulum (ER) supports biosynthesis of proteins
with diverse transmembrane domain (TMD) lengths and hydrophobicity. Features in …

[PDF][PDF] Mapping transcriptomic vector fields of single cells

…, MY Hein, KHJ Min, L Wang, EI Grody, MJ Shurtleff… - Cell, 2022 - cell.com
Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular
states and transitions at unprecedented resolution. Fully exploiting these data, however, …

[BOOK][B] Audition

M Shurtleff - 1979 - books.google.com
… Michael Shurtleff knows exactly where you can find that dream; his Twelve Guideposts will
… as long as possible) about what I would like to say about Michael Shurtleff and this book. …

Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients

…, JR Prabu, EA Boydston, N Sevillano, MJ Shurtleff… - elife, 2020 - elifesciences.org
Membrane protein biogenesis in the endoplasmic reticulum (ER) is complex and failure-prone.
The ER membrane protein complex (EMC), comprising eight conserved subunits, has …