This consensus document is intended to serve 3 functions. First, it standardizes the criteria
for diagnosis of chronic graft-versus-host disease (GVHD). Second, it proposes a new clinical …

Nearly all cell surface receptors utilize one or more of the mitogen-activated protein kinase
cascades in their repertoire of signal transduction mechanisms. Recent advances in the study …

Background: Millions of patients are discharged from intensive care units annually. These
intensive care survivors and their families frequently report a wide range of impairments in …

Background In 2010, overweight and obesity were estimated to cause 3·4 million deaths, 3·9%
of years of life lost, and 3·8% of disability-adjusted life-years (DALYs) worldwide. The rise …

… We use the NB parameterization where the mean is μ gi =M i p gj and variance is μ gi (1+μ
gi ϕ g ). For differential expression analysis, the parameters of interest are p gj . …

We report here the adoptive transfer, to patients with metastatic melanoma, of highly selected
tumor-reactive T cells directed against overexpressed self-derived differentiation antigens …

Identification of protein–protein interactions often provides insight into protein function, and
many cellular processes are performed by stable protein complexes. We used tandem affinity …

Background The comparative effectiveness of treatments for prostate cancer that is detected
by prostate-specific antigen (PSA) testing remains uncertain. Methods We compared active …

… To robustly summarize the observed M values, we trim both the M values and the A values
… However, we illustrate with M versus A plots that their normalization does not completely …

Background There is growing evidence that faecal-occult-blood (FOB) screening may reduce
colorectal cancer (CRC) mortality, but this reduction in CRC mortality has not been shown …