Allosteric regulation is found across all domains of life, yet we still lack simple, predictive
theories that directly link the experimentally tunable parameters of a system to its input-output …

It is tempting to believe that we now own the genome. The ability to read and rewrite it at will
has ushered in a stunning period in the history of science. Nonetheless, there is an Achilles’ …

… copy number m, given that it had copy number m′ before the burst. The fourth term allows
the system to start with copy number m, then produce a burst and end with copy number m′. …

Mutation is a critical mechanism by which evolution explores the functional landscape of
proteins. Despite our ability to experimentally inflict mutations at will, it remains difficult to link …

… (m, p;t), where m and p are the mRNA and protein count per cell, respectively, and t is time.
Given the rates depicted in Fig. 2(a) we define the system of ODEs for a specific m … P(m, p) as …

… where γ is the mRNA degradation rate and m is the number of transcripts of the gene per cell;
… became noticeably yellow, we stopped the reaction by adding 200 μL of 2.5 M Na 2 CO 3 . …

Apart from addressing humanity’s growing demand for fuels, pharmaceuticals, plastics and
other value added chemicals, metabolic engineering of microbes can serve as a powerful …

… Our data consists of an T × B matrix , where B = M + N is the number of unique barcodes
given by the sum of the number of unique, relevant barcodes we care about, M, and the number …

The rapid turnover of dimethylsulfoniopropionate (DMSP), likely the most relevant dissolved
organic sulfur compound in the surface ocean, makes it pivotal to understand the cycling of …

… at the state p(m) from a state with one fewer mRNA, namely p(m - 1), and RD describes
probability flux departing from the state p(m) for a state with one more mRNA, namely p(m + 1). K …