BACKGROUND The majority of Chlamydia trachomatis infections in women are asymptomatic,
but may give rise to pelvic inflammatory disease (PID) and tubal infertility. Screening …

Introduction Asthma, allergic rhinitis, atopic dermatitis, and food allergy affect approximately
20% of the global population. Few studies describe the burden of the totality of these …

The treatment of chronic kidney disease (CKD) and of end-stage renal disease (ESRD)
imposes substantial societal costs. Expenditure is highest for renal replacement therapy (RRT), …

Background Neurological disorders are now the leading source of disability globally, and
ageing is increasing the burden of neurodegenerative disorders, including Parkinson's disease…

Importance The increasing burden due to cancer and other noncommunicable diseases
poses a threat to human development, which has resulted in global political commitments …

We report the engineering of mScarlet, a truly monomeric red fluorescent protein with record
brightness, quantum yield (70%) and fluorescence lifetime (3.9 ns). We developed mScarlet …

Introduction Multiple myeloma (MM) is a plasma cell neoplasm with substantial morbidity and
mortality. A comprehensive description of the global burden of MM is needed to help direct …

Background Lower respiratory infections are a leading cause of morbidity and mortality around
the world. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study 2016, …

In this paper we discuss a new generalized time-dependent Ginzburg-Landau theory for the
numerical calculation of polymer phase separation kinetics in 3D. The thermodynamic …

Background It is unknown whether patients undergoing primary percutaneous coronary
intervention (PCI) benefit from genotype-guided selection of oral P2Y 12 inhibitors. Methods We …