Background Biological interpretation of gene/protein lists resulting from -omics experiments
can be a complex task. A common approach consists of reviewing Gene Ontology (GO) …

Background The three-dimensional organization of the genome is tightly connected to its
biological function. The Hi-C approach was recently introduced as a method that can be used …

Tuberculosis (TB) is a major infectious disease worldwide, and is associated with several
challenges for control and eradication. First, more accurate diagnostic tools that better …

10.7554/eLife.46045.001 Our results highlight for the first time that a significant proportion of
cell doublets in flow cytometry, previously believed to be the result of technical artifacts and …

… However, we expect the prevalence of circulating M. tuberculosis–specific effector T cells
to be increased in ATB, which is marked by a lack of control of M. tuberculosis and thus …

Our recent work has highlighted that care needs to be taken when interpreting single cell data
originating from flow cytometry acquisition or cell sorting: We found that doublets of T cells …

Opisthorchis felineus, the trematode belonging to the family Opisthorchiidae, is a causative
agent of the infection called opisthorchiasis or liver fluke infection. Being a close relative of …

CD8 T cells are considered important contributors to the immune response against
Mycobacterium tuberculosis, yet limited information is currently known regarding their specific …

The increased incidence of whooping cough worldwide suggests that current vaccination
against Bordetella pertussis infection has limitations in quality and duration of protection. The …

The epidemiologically important liver flukes Opisthorchis felineus, Opisthorchis viverrini, and
Clonorchis sinensis are of interest to health professionals, epidemiologists, pharmacologists…