Many of the cancers common in the Western world, including colon, prostate and breast
cancers, are thought to relate to dietary habits. Of the known risk factors, many will act through …

P2X7 is a transmembrane receptor expressed in multiple cell types including neurons,
dendritic cells, macrophages, monocytes, B and T cells where it can drive a wide range of …

Epigenetic proteins are intently pursued targets in ligand discovery. So far, successful efforts
have been limited to chromatin modifying enzymes, or so-called epigenetic ‘writers’ and ‘…

… The technical help of Antje Winter-Keil, Claudia Kremling and Gabriele Scheel and the
expertise of the entire Paus and Philpott laboratory teams in the day-to-day use of human HFOC …

For a long time, the mantra of acne pathogenesis debates has been that acne vulgaris lesions
develop when (supposedly largely androgen‐mediated) increased sebum production, …

We report for the first time the successful maintenance and growth of human hair follicles in
vitro. Human anagen hair follicles were isolated by microdissection from human scalp skin. …

… The pair of oligonucleotides were annealed in a buffer (75 mm NaCl, 5 mm Tris-HCl, and
0.5 mm EDTA) and heated to 95C, followed by gradual cooling to 25C in a heating block. The …

… To establish a selectivity profile for RVX-208, we used temperature-shift assays (ΔT m )
carried out on 44 of the 61 human bromodomains and found that its effect on BRD temperature …

Insulin stimulated hair follicle growth in a dose-dependent manner over the range of 0.01 to
100 μg/ml. Maximum rates of hair follicle growth were observed when follicles were …

Because the surface plasmon resonance is a sensitive probe of metallic surfaces we have
measured quantitatively the changes that occur in surface plasmon resonances from coatings …