Background Artemisinin resistance in Plasmodium falciparum has emerged in Southeast Asia
and now poses a threat to the control and elimination of malaria. Mapping the geographic …

Background Severe malaria is a major cause of childhood death and often the main reason
for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established …

We report a large multicenter genome-wide association study of Plasmodium falciparum
resistance to artemisinin, the frontline antimalarial drug. Across 15 locations in Southeast Asia, …

Artemisinin resistance in Plasmodium falciparum threatens global efforts to control and
eliminate malaria. Polymorphisms in the kelch domain–carrying protein K13 are associated with …

Background Artemisinin and partner-drug resistance in Plasmodium falciparum are major
threats to malaria control and elimination. Triple artemisinin-based combination therapies (…

Background. Data from the largest randomized, controlled trial for the treatment of children
hospitalized with severe malaria were used to identify such predictors of a poor outcome from …

Objectives. We examined pregnant women's use of cigarettes and other tobacco products and
the exposure of pregnant women and their young children to secondhand smoke (SHS) in …

A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …

Background: National Malaria Control Programmes (NMCPs) currently make limited use of
parasite genetic data. We have developed GenRe-Mekong, a platform for genetic …

We describe the MalariaGEN Pf7 data resource, the seventh release of Plasmodium falciparum
genome variation data from the MalariaGEN network. It comprises over 20,000 samples …