User profiles for M. Muelleder

Michael Mülleder

Charité – Universitätsmedizin Berlin, Core Facility - High Throughput Mass Spectrometry
Verified email at charite.de
Cited by 4075

[HTML][HTML] Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19

…, J Kazmierski, F Pott, K Dietert, M Muelleder… - Nature …, 2021 - nature.com
In COVID-19, immune responses are key in determining disease severity. However, cellular
mechanisms at the onset of inflammatory lung injury in SARS-CoV-2 infection, particularly …

[PDF][PDF] THADA regulates the organismal balance between energy storage and heat production

…, M Males, S Mueller, M Jabs, M Muelleder, M Frejno… - Developmental Cell, 2017 - cell.com
Human susceptibility to obesity is mainly genetic, yet the underlying evolutionary drivers
causing variation from person to person are not clear. One theory rationalizes that populations …

Role of the complement system in Long COVID

…, LG Hanitsch, M Witzenrath, F Kurth, M Muelleder… - medRxiv, 2024 - medrxiv.org
Long COVID, or Post-Acute COVID Syndrome (PACS), may develop following SARS-CoV-2
infection, posing a substantial burden to society. Recently, PACS has been linked to a …

Low Blood Levels of Selenium, Selenoprotein P and GPx3 are Associated with Accelerated Biological Aging: Results from the Berlin Aging Study II (BASE-II)

…, K Demircan, J Homann, TS Chillon, M Muelleder… - medRxiv, 2024 - medrxiv.org
Introduction Biological age reflects inter-individual differences in biological function and
capacity beyond chronological age. Biological age can be estimated by DNA methylation age (…

The amino acid sequence determines protein abundance through its conformational stability and reduced synthesis cost.

…, O Lemke, J Zrimec, L Szyrwiel, M Muelleder, M Ralser… - bioRxiv, 2023 - biorxiv.org
Understanding what drives protein abundance is essential to biology, medicine, and
biotechnology. Driven by evolutionary selection, the amino acid sequence is tailored to meet the …

The molecular landscape of cellular metal ion biology

…, Y Chen, J Hartl, M Muelleder, J Nielsen, M Ralser - bioRxiv, 2024 - biorxiv.org
Metal ions play crucial roles in cells, yet the broader impact of metal availability on biological
networks remains underexplored. We generated genome-wide resources, systematically …

Myeloperoxidase-dependent tyrosine halogenation potentiates alpha-defensins functions

…, M Muelleder, A Biswas, P Fahjen, M Winkler… - bioRxiv, 2023 - biorxiv.org
Neutrophils are immune cells specialized in detecting and eliminating microbes through
potent cytotoxic mechanisms. Most of the neutrophil antimicrobial proteins are stored in …

Role of the complement system in Long COVID (preprint)

…, LG Hanitsch, M Witzenrath, F Kurth, M Muelleder… - 2024 - pesquisa.bvsalud.org
Long COVID, or Post-Acute COVID Syndrome (PACS), may develop following SARS-CoV-2
infection, posing a substantial burden to society. Recently, PACS has been linked to a …

Speedy-PASEF: Analytical flow rate chromatography and trapped ion mobility for deep high-throughput proteomics (preprint)

L Szyrwiel, C Gille, M Muelleder, V Demichev, M Ralser - 2023 - pesquisa.bvsalud.org
Increased throughput in proteomic experiments can improve accessibility of proteomic platforms,
reduce costs and facilitate new approaches in systems biology and biomedical research…

Single-cell-sequencing in SARS-COV-2-infected hamsters sheds light on endothelial cell involvement in COVID-19

…, J Kazmierski, F Pott, K Dietert, M Muelleder… - 2021 - Eur Respiratory Soc
Background: Pulmonary and systemic immune responses influence disease severity in
COVID-19, and could be key to therapeutic strategies. Aims and objectives: To investigate …