User profiles for M. Mhlanga

musa m. mhlanga

Professor, Radboud Institute for Molecular Life Sciences,
Verified email at mhlangalab.org
Cited by 9035

[HTML][HTML] Defining trained immunity and its role in health and disease

…, JWM van der Meer, MM Mhlanga… - Nature Reviews …, 2020 - nature.com
Immune memory is a defining feature of the acquired immune system, but activation of the
innate immune system can also result in enhanced responsiveness to subsequent triggers. …

[PDF][PDF] The intersection of epigenetics and metabolism in trained immunity

…, LAB Joosten, MG Netea, MM Mhlanga - Immunity, 2021 - cell.com
The last few years have witnessed an increasing body of evidence that challenges the
traditional view that immunological memory is an exclusive trait of the adaptive immune system. …

PALM and STORM: unlocking live‐cell super‐resolution

…, C Griffiths, E Hesper Rego, MM Mhlanga - …, 2011 - Wiley Online Library
Live‐cell fluorescence light microscopy has emerged as an important tool in the study of
cellular biology. The development of fluorescent markers in parallel with super‐resolution …

The human cell atlas

…, JC Marioni, M Merad, M Mhlanga, M Nawijn, M Netea… - elife, 2017 - elifesciences.org
10.7554/eLife.27041.001 The recent advent of methods for high-throughput single-cell
molecular profiling has catalyzed a growing sense in the scientific community that the time is ripe …

[HTML][HTML] Trained immunity, tolerance, priming and differentiation: distinct immunological processes

…, G Matarese, JWM van der Meer, M Mhlanga… - Nature …, 2021 - nature.com
The similarities and differences between trained immunity and other immune processes are
the subject of intense interrogation. Therefore, a consensus on the definition of trained …

QuickPALM: 3D real-time photoactivation nanoscopy image processing in ImageJ

…, EF Fornasiero, F Valtorta, C Zimmer, MM Mhlanga - Nature …, 2010 - nature.com
To the Editor: Although conventional microscopes have a resolution limited by diffraction to
about half the wavelength of light, several recent advances have led to microscopy methods …

Visualizing the distribution and transport of mRNAs in living cells

DP Bratu, BJ Cha, MM Mhlanga… - Proceedings of the …, 2003 - National Acad Sciences
We have visualized the movements of native mRNAs in living cells. Using nuclease-resistant
molecular beacons, we imaged the transport and localization of oskar mRNA in Drosophila …

Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation

…, DM Lang, R Hurdayal, MM Mhlanga… - The Journal of …, 2014 - academic.oup.com
Background. Statins are cholesterol-lowering drugs, targeting HMG-CoA reductase, thereby
reducing the risk of coronary disorders and hypercholesterolemia. However, they also can …

Spectral genotyping of human alleles

LG Kostrikis, S Tyagi, MM Mhlanga, DD Ho, FR Kramer - Science, 1998 - science.org
Accelerated by the human genome project [HN1], an increasing number of genetic variations,
many as small as a single nucleotide substitution [HN2], have been found to play a …

TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures

…, B Boisson, R Henriques, M Mhlanga… - Journal of Cell …, 2014 - rupress.org
Nuclear factor κB (NF-κB) essential modulator (NEMO), a regulatory component of the IκB
kinase (IKK) complex, controls NF-κB activation through its interaction with ubiquitin chains. …