User profiles for M. Mhlanga
musa m. mhlangaProfessor, Radboud Institute for Molecular Life Sciences, Verified email at mhlangalab.org Cited by 9035 |
[HTML][HTML] Defining trained immunity and its role in health and disease
…, JWM van der Meer, MM Mhlanga… - Nature Reviews …, 2020 - nature.com
Immune memory is a defining feature of the acquired immune system, but activation of the
innate immune system can also result in enhanced responsiveness to subsequent triggers. …
innate immune system can also result in enhanced responsiveness to subsequent triggers. …
[PDF][PDF] The intersection of epigenetics and metabolism in trained immunity
The last few years have witnessed an increasing body of evidence that challenges the
traditional view that immunological memory is an exclusive trait of the adaptive immune system. …
traditional view that immunological memory is an exclusive trait of the adaptive immune system. …
PALM and STORM: unlocking live‐cell super‐resolution
…, C Griffiths, E Hesper Rego, MM Mhlanga - …, 2011 - Wiley Online Library
Live‐cell fluorescence light microscopy has emerged as an important tool in the study of
cellular biology. The development of fluorescent markers in parallel with super‐resolution …
cellular biology. The development of fluorescent markers in parallel with super‐resolution …
The human cell atlas
10.7554/eLife.27041.001 The recent advent of methods for high-throughput single-cell
molecular profiling has catalyzed a growing sense in the scientific community that the time is ripe …
molecular profiling has catalyzed a growing sense in the scientific community that the time is ripe …
[HTML][HTML] Trained immunity, tolerance, priming and differentiation: distinct immunological processes
…, G Matarese, JWM van der Meer, M Mhlanga… - Nature …, 2021 - nature.com
The similarities and differences between trained immunity and other immune processes are
the subject of intense interrogation. Therefore, a consensus on the definition of trained …
the subject of intense interrogation. Therefore, a consensus on the definition of trained …
QuickPALM: 3D real-time photoactivation nanoscopy image processing in ImageJ
To the Editor: Although conventional microscopes have a resolution limited by diffraction to
about half the wavelength of light, several recent advances have led to microscopy methods …
about half the wavelength of light, several recent advances have led to microscopy methods …
Visualizing the distribution and transport of mRNAs in living cells
DP Bratu, BJ Cha, MM Mhlanga… - Proceedings of the …, 2003 - National Acad Sciences
We have visualized the movements of native mRNAs in living cells. Using nuclease-resistant
molecular beacons, we imaged the transport and localization of oskar mRNA in Drosophila …
molecular beacons, we imaged the transport and localization of oskar mRNA in Drosophila …
Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation
…, DM Lang, R Hurdayal, MM Mhlanga… - The Journal of …, 2014 - academic.oup.com
Background. Statins are cholesterol-lowering drugs, targeting HMG-CoA reductase, thereby
reducing the risk of coronary disorders and hypercholesterolemia. However, they also can …
reducing the risk of coronary disorders and hypercholesterolemia. However, they also can …
Spectral genotyping of human alleles
Accelerated by the human genome project [HN1], an increasing number of genetic variations,
many as small as a single nucleotide substitution [HN2], have been found to play a …
many as small as a single nucleotide substitution [HN2], have been found to play a …
TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures
Nuclear factor κB (NF-κB) essential modulator (NEMO), a regulatory component of the IκB
kinase (IKK) complex, controls NF-κB activation through its interaction with ubiquitin chains. …
kinase (IKK) complex, controls NF-κB activation through its interaction with ubiquitin chains. …