Chromosomes of a broad range of species, from bacteria to mammals, are structured by
large topological domains whose precise functional roles and regulatory mechanisms remain …

As in eukaryotes, bacterial genomes are not randomly folded. Bacterial genetic information
is generally carried on a circular chromosome with a single origin of replication from which …

Background Chromatin organization has been increasingly studied in relation with its important
influence on DNA-related metabolic processes such as replication or regulation of gene …

… Marbouty et al. took advantage of these interactions to develop a technique that combines
metagenomics and chromosome conformation capture—called meta3C—that can analyze the …

Closing gaps in draft genome assemblies can be costly and time-consuming, and published
genomes are therefore often left ‘unfinished.’ Here we show that genome-wide …

Bacteria with multiple chromosomes represent up to 10% of all bacterial species. Unlike
eukaryotes, these bacteria use chromosome-specific initiators for their replication. In all cases …

… the genetic content of the community, as well as the clustering and scaffolding steps that
will provide a glimpse of the genomic structure of the population [reviewed by Marbouty and …

Bdelloid rotifers are notorious as a speciose ancient clade comprising only asexual lineages.
Thanks to their ability to repair highly fragmented DNA, most bdelloid species also …

Bacteriophages play important roles in regulating the intestinal human microbiota
composition, dynamics, and homeostasis, and characterizing their bacterial hosts is needed to …

Background The spatiotemporal behavior of chromatin is an important control mechanism of
genomic function. Studies in Saccharomyces cerevisiae have broadly contributed to …