Molecular signatures of obstructive sleep apnea in adults: a review and perspective
ES Arnardottir, M Mackiewicz, T Gislason, KL Teff… - Sleep, 2009 - academic.oup.com
The consequences of obstructive sleep apnea (OSA) are largely mediated by chronic
intermittent hypoxia and sleep fragmentation. The primary molecular domains affected are …
intermittent hypoxia and sleep fragmentation. The primary molecular domains affected are …
Recent advances in the redox-responsive drug delivery nanoplatforms: A chemical structure and physical property perspective
…, M Mackiewicz, M Yazdimamaghani - Materials Science and …, 2021 - Elsevier
Poor water solubility, off-target toxicity, and small therapeutic window are among major
obstacles for the development of drug products. Redox-responsive drug delivery nanoplatforms …
obstacles for the development of drug products. Redox-responsive drug delivery nanoplatforms …
[HTML][HTML] Expanded encyclopaedias of DNA elements in the human and mouse genomes
The human and mouse genomes contain instructions that specify RNAs and proteins and
govern the timing, magnitude, and cellular context of their production. To better delineate these …
govern the timing, magnitude, and cellular context of their production. To better delineate these …
The Beaker phenomenon and the genomic transformation of northwest Europe
From around 2750 to 2500 bc, Bell Beaker pottery became widespread across western and
central Europe, before it disappeared between 2200 and 1800 bc. The forces that propelled …
central Europe, before it disappeared between 2200 and 1800 bc. The forces that propelled …
Self-ensembling for visual domain adaptation
G French, M Mackiewicz, M Fisher - arXiv preprint arXiv:1706.05208, 2017 - arxiv.org
This paper explores the use of self-ensembling for visual domain adaptation problems. Our
technique is derived from the mean teacher variant (Tarvainen et al., 2017) of temporal …
technique is derived from the mean teacher variant (Tarvainen et al., 2017) of temporal …
Molecular mechanisms of sleep and wakefulness
M Mackiewicz, N Naidoo… - Annals of the New …, 2008 - Wiley Online Library
Major questions on the biology of sleep include the following: what are the molecular
functions of sleep; why can wakefulness only be sustained for defined periods before there is …
functions of sleep; why can wakefulness only be sustained for defined periods before there is …
Macromolecule biosynthesis: a key function of sleep
M Mackiewicz, KR Shockley, MA Romer… - Physiological …, 2007 - journals.physiology.org
The function(s) of sleep remains a major unanswered question in biology. We assessed
changes in gene expression in the mouse cerebral cortex and hypothalamus following different …
changes in gene expression in the mouse cerebral cortex and hypothalamus following different …
Semi-supervised semantic segmentation needs strong, varied perturbations
… As in [13] we initialize a mask M with the value 1 and set the pixels inside a randomly … the
input pixels with M and disregard the consistency loss for pixels masked to 0 by M. FixMatch [38…
input pixels with M and disregard the consistency loss for pixels masked to 0 by M. FixMatch [38…
Brain glycogen decreases with increased periods of wakefulness: implications for homeostatic drive to sleep
…, PN Shepel, CP Holden, M Mackiewicz… - Journal of …, 2002 - Soc Neuroscience
Sleep is thought to be restorative in function, but what is restored during sleep is unclear.
Here we tested the hypothesis that increased periods of wakefulness will result in decreased …
Here we tested the hypothesis that increased periods of wakefulness will result in decreased …
Color correction using root-polynomial regression
GD Finlayson, M Mackiewicz… - IEEE Transactions on …, 2015 - ieeexplore.ieee.org
… If data is represented by a vector X of m unique measurements then an m-degree polynomial
expansion of X will span mdimensional space and so X can be related to any other variable…
expansion of X will span mdimensional space and so X can be related to any other variable…