Metronidazole, the prototype nitroimidazole antimicrobial, was originally introduced to treat
Trichomonas vaginalis, but is now used for the treatment of anaerobic and protozoal …

… Although the presence of an M protein is the hallmark of myeloma, 1% to 2% of patients will
have nonsecretory myeloma with no M protein detectable on serum or urine electrophoresis …

Vaccine adjuvants based on the structure of lipid A, such as monophosphoryl lipid A (MLA),
have proven to be safe and effective in inducing immune responses to heterologous proteins …

… Channels 1 (3.6 m) and 2 (4.5 m) InSb detector arrays operate at a temperature of 15 K,
and channels 3 (5.8 m) and 4 (8.0 m) Si:As detector arrays operate at 6 K. To help achieve the …

… In 1 of the 7 patients with a serum M-protein, a small IgG k M-protein and subsequently a
small IgG λ M-protein developed after autologous stem cell transplantation. The 2 M-proteins …

Treatments for myeloma have expanded in the last decade, but it is not clear if the introduction
of novel therapies and the increased use of high-dose therapy have translated into better …

Transposon inactivation of Arabidopsis MAP kinase 4 produced the mpk4 mutant exhibiting
constitutive systemic acquired resistance (SAR) including elevated salicylic acid (SA) levels, …

Therapy for multiple myeloma (MM) has markedly changed in the past decade with the
introduction of new drugs, but it is not clear whether the improvements have been sustained. We …

The POEMS syndrome (coined to refer to polyneuropathy, organomegaly, endocrinopathy,
M protein, and skin changes) remains poorly understood. Ambiguity exists over the features …

Background Few effective treatments exist for patients with refractory or relapsed and
refractory multiple myeloma not responding to treatment with bortezomib and lenalidomide. …