User profiles for M. Kaakinen
Marika A KaakinenVisiting researcher, Imperial College London Verified email at imperial.ac.uk Cited by 29673 |
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption
…, I Barroso, I Johansson, L Xue, M Kaakinen… - Molecular …, 2015 - nature.com
Coffee, a major dietary source of caffeine, is among the most widely consumed beverages in
the world and has received considerable attention regarding health risks and benefits. We …
the world and has received considerable attention regarding health risks and benefits. We …
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic
traits, we performed meta-analyses of 21 genome-wide association studies informative for …
traits, we performed meta-analyses of 21 genome-wide association studies informative for …
[HTML][HTML] Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts
Background Obesity is associated with vitamin D deficiency, and both are areas of active
public health concern. We explored the causality and direction of the relationship between …
public health concern. We explored the causality and direction of the relationship between …
Genome-wide association study identifies 74 loci associated with educational attainment
Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …
Common variants associated with plasma triglycerides and risk for coronary artery disease
Triglycerides are transported in plasma by specific triglyceride-rich lipoproteins; in
epidemiological studies, increased triglyceride levels correlate with higher risk for coronary artery …
epidemiological studies, increased triglyceride levels correlate with higher risk for coronary artery …
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
A genome-wide association study (GWAS) of educational attainment was conducted in a
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
Variants in MTNR1B influence fasting glucose levels
To identify previously unknown genetic loci associated with fasting glucose concentrations,
we examined the leading association signals in ten genome-wide association scans …
we examined the leading association signals in ten genome-wide association scans …
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
Very few genetic variants have been associated with depression and neuroticism, likely
because of limitations on sample size in previous studies. Subjective well-being, a phenotype …
because of limitations on sample size in previous studies. Subjective well-being, a phenotype …
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population
…, CG Jones, NA Zaitlen, T Varilo, M Kaakinen… - Nature …, 2009 - nature.com
Genome-wide association studies (GWAS) of longitudinal birth cohorts enable joint investigation
of environmental and genetic influences on complex traits. We report GWAS results for …
of environmental and genetic influences on complex traits. We report GWAS results for …