The pacemaking activity of specialized tissues in the heart and gut results in lifelong rhythmic
contractions. Here we describe a new syndrome characterized by Chronic Atrial and …

Since their origin, human populations have colonized the whole planet, but the demographic
processes governing range expansions are mostly unknown. We analyzed the genealogy …

… Migration rate was set to m = 0.2 and the within-deme growth rate was R = 2 [that is, at
low densities the population doubles within one generation, reflecting the average absolute …

The Saguenay–Lac St-Jean population of Quebec is relatively isolated and has genealogical
records dating to the 17th-century French founders. In 120 extended families with at least …

… demonstrating that Canadian adults with BMI ≥27 kg/m 2 have nearly twice the prevalence
of hypertension than those with BMI <27 kg/m 2 . In the selected “obese” families, the …

The predominance of the T14484C mutation in French Canadians with Leber hereditary optic
neuropathy is due to a founder effect. By use of genealogical reconstructions of maternal …

… The prevalence of obesity (BMI ≥ 27 kg/m 2 ) among Canadian men and women affected
… overweight (BMI = 28.36 ± 0.30 kg/m 2 ). Their mean fasting triglycerides were within the …

… An individual separated by m meioses from an ancestor is expected to share 2 −m of this
ancestor’s genome, ie on average about 0.1%, or 3.3 cM, after 10 generations. However, the …

… Lesirzsii off from M. murex as a new species; Small (19866) reduced M. dzhawakhetica
to a form without taxonomic significance and recognized two well-defined geographical …

Data from uniparentally inherited genetic systems were used to trace evolution of human
populations. Reconstruction of the past primarily relies on variation in present‐day populations, …