The European mountain cryosphere: a review of its current state, trends, and future challenges
The mountain cryosphere of mainland Europe is recognized to have important impacts on a
range of environmental processes. In this paper, we provide an overview on the current …
range of environmental processes. In this paper, we provide an overview on the current …
A primer on deep learning in genomics
Deep learning methods are a class of machine learning techniques capable of identifying
highly complex patterns in large datasets. Here, we provide a perspective and primer on deep …
highly complex patterns in large datasets. Here, we provide a perspective and primer on deep …
Toward mountains without permanent snow and ice
… We quantify mass fluxes (F) and the mass of reservoirs (M) related to mountain hydrology
at the global scale based on published literature. All fluxes are estimates that are subject to …
at the global scale based on published literature. All fluxes are estimates that are subject to …
[HTML][HTML] Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics
…, M Zwahlen, IM Olsson, S Navani, M Huss… - Molecular & cellular …, 2014 - ASBMB
Global classification of the human proteins with regards to spatial expression patterns across
organs and tissues is important for studies of human biology and disease. Here, we used a …
organs and tissues is important for studies of human biology and disease. Here, we used a …
[HTML][HTML] Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
Transcription factors (TFs) and their specific interactions with targets are crucial for specifying
gene-expression programs. To gain insights into the transcriptional regulatory networks in …
gene-expression programs. To gain insights into the transcriptional regulatory networks in …
Visualization and analysis of gene expression in tissue sections by spatial transcriptomics
Analysis of the pattern of proteins or messengerRNAs (mRNAs) in histological tissue
sections is a cornerstone in biomedical research and diagnostics. This typically involves the …
sections is a cornerstone in biomedical research and diagnostics. This typically involves the …
Accelerated global glacier mass loss in the early twenty-first century
… × 500 m that we down-sampled to a resolution of 50 m to limit repeat spatial sampling when
comparing to the 100 m resolution of our elevation time series. We linearly interpolated our …
comparing to the 100 m resolution of our elevation time series. We linearly interpolated our …
Global glacier mass changes and their contributions to sea-level rise from 1961 to 2016
… m we = 1,000 kg m −2 ). The least negative specific mass changes were found for glaciers in
the Antarctic periphery (−0.1 m … m we for the specific mass change (1 m we = 1,000 kg m −2 …
the Antarctic periphery (−0.1 m … m we for the specific mass change (1 m we = 1,000 kg m −2 …
[PDF][PDF] Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst
Three distinct cell types are present within the 64-cell stage mouse blastocyst. We have
investigated cellular development up to this stage using single-cell expression analysis of more …
investigated cellular development up to this stage using single-cell expression analysis of more …
Global-scale hydrological response to future glacier mass loss
Worldwide glacier retreat and associated future runoff changes raise major concerns over
the sustainability of global water resources 1 , 2 , 3 – 4 , but global-scale assessments of …
the sustainability of global water resources 1 , 2 , 3 – 4 , but global-scale assessments of …