determination and the implementation of preventive, diagnostic or therapeutic medical
strategies. However, the ESC Guidelines do not override in any way whatsoever the individual …

… MV Huisman has received unrestricted grant support from Boehringer Ingelheim and GSK
for … MV Huisman critically revised the paper for important intellectual content. All authors …

… Author Contributions: Mr Snoep and Drs Hovens and Huisman had full access to all the data
in the study and take responsibility for the integrity of the data and the accuracy of the data …

… Menno Huisman reports grants from ZonMW Dutch Healthcare Fund, and grants and
personal fees from Boehringer-Ingelheim, Pfizer-BMS, Bayer Health Care, Aspen, Daiichi-Sankyo, …

The task of developing ESC Guidelines covers not only the integration of the most recent
research, but also the creation of educational tools and implementation programmes for the …

Background We update recommendations on 12 topics that were in the 9th edition of these
guidelines, and address 3 new topics. Methods We generate strong (Grade 1) and weak (…

Introduction We recently reported a high cumulative incidence of thrombotic complications in
critically ill patients with COVID-19 admitted to the intensive care units (ICUs) of three Dutch …

In 220 consecutive outpatients with clinically suspected deep-vein thrombosis of the leg, we
compared contrast venography with real-time B-mode ultrasonography, using the single …

Background Specific reversal agents for non–vitamin K antagonist oral anticoagulants are
lacking. Idarucizumab, an antibody fragment, was developed to reverse the anticoagulant …

Background This phase 3 trial compared the efficacy and safety of rivaroxaban, an oral direct
inhibitor of factor Xa, with those of enoxaparin for extended thromboprophylaxis in patients …