The mononuclear phagocyte system (MPS) has historically been categorized into monocytes,
dendritic cells and macrophages on the basis of functional and phenotypical characteristics…

Defining the origins and developmental pathways of tissue-resident macrophages should
help refine our understanding of the role of these cells in various disease settings and enable …

Novel experimental approaches such as fate-mapping and single-cell analysis have brought
fresh insight into monocyte development and function over the past decade and helped …

Mononuclear phagocytes, including monocytes, macrophages, and dendritic cells, contribute
to tissue integrity as well as to innate and adaptive immune defense. Emerging evidence …

The induction of CD11b + Gr-1 + myeloid-derived suppressor cells (MDSCs) is an important
immune-evading mechanism used by tumors. However, the exact nature and function of …

Dendritic cells (DCs) are crucial for mounting allergic airway inflammation, but it is unclear
which subset of DCs performs this task. By using CD64 and MAR-1 staining, we reliably …

… , by a Marie Curie re-integration grant (CIG), a Belspo Return Grant, a Post-Doc FWO
grant and a Odysseus Grant to M. Guilliams, and by a FWO project grant to H. Hammad. I. …

The liver is the largest solid organ in the body, yet it remains incompletely characterized.
Here we present a spatial proteogenomic atlas of the healthy and obese human and murine …

In the skin, the lack of markers permitting the unambiguous identification of macrophages and
of conventional and monocyte-derived dendritic cells (DCs) complicates understanding of …

Macrophages (mϕ) are essential for intestinal homeostasis and the pathology of inflammatory
bowel disease (IBD), but it is unclear whether discrete mϕ populations carry out these …