Better biomarkers are urgently needed to improve diagnosis, guide molecularly targeted
therapy and monitor activity and therapeutic response across a wide spectrum of disease. …

Targeted mass spectrometry (MS) is becoming widely used in academia and in pharmaceutical
and biotechnology industries for sensitive and quantitative detection of proteins, …

Genomic analyses in cancer have been enormously impactful, leading to the identification
of driver mutations and development of targeted therapies. But the functions of the vast …

We have generated a molecular taxonomy of lung carcinoma, the leading cause of cancer
death in the United States and worldwide. Using oligonucleotide microarrays, we analyzed …

Although genomewide RNA expression analysis has become a routine tool in biomedical
research, extracting biological insight from such information remains a major challenge. Here, …

Gate-model quantum computers promise to solve currently intractable computational problems
if they can be operated at scale with long coherence times and high-fidelity logic. Neutral-…

Somatic mutations have been extensively characterized in breast cancer, but the effects of
these genetic alterations on the proteomic landscape remain poorly understood. Here we …

In his groundbreaking work, Martin Haberman identified key dispositions of “star” teachers
that help them work successfully with students in poverty. More than two decades later, …

To provide a detailed analysis of the molecular components and underlying mechanisms
associated with ovarian cancer, we performed a comprehensive mass-spectrometry-based …

To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and …