Multiple roles of PIWIL1 in mouse neocorticogenesis
…, SHR Wijeratne, R Kristopovich, M Dutre-Clarke… - bioRxiv, 2017 - biorxiv.org
PIWI-interacting RNAs (piRNAs) and their associated PIWI proteins play an important role in
repressing transposable elements in animal germlines. However, little is known about the …
repressing transposable elements in animal germlines. However, little is known about the …
Hippocampal knockdown of Piwil1 and Piwil2 enhances contextual fear memory in mice
The Piwi pathway is a conserved gene regulatory mechanism comprised of Piwi-like proteins
and Piwi-interacting RNAs, which modulates gene expression via RNA interference and …
and Piwi-interacting RNAs, which modulates gene expression via RNA interference and …
[PDF][PDF] Piwil1 regulates glioma stem cell maintenance and glioblastoma progression
Piwi proteins are a subfamily of Argonaute proteins that maintain germ cells in eukaryotes.
However, the role of their human homologs in cancer stem cells, and more broadly in cancer, …
However, the role of their human homologs in cancer stem cells, and more broadly in cancer, …
A functional role for the epigenetic regulator ING1 in activity-induced gene expression in primary cortical neurons
Epigenetic regulation of activity-induced gene expression involves multiple levels of molecular
interaction, including histone and DNA modifications, as well as mechanisms of DNA …
interaction, including histone and DNA modifications, as well as mechanisms of DNA …
[HTML][HTML] Molecular and functional characterization of the somatic PIWIL1/piRNA pathway in colorectal cancer cells
… fraction; nuclei were resuspended in 0.34 M sucrose and centrifuged at 2000× g for 10 min
in order to remove contaminants; nuclei were finally lysed in 8 M urea and sonicated 3 times (…
in order to remove contaminants; nuclei were finally lysed in 8 M urea and sonicated 3 times (…
[HTML][HTML] Functional interplay between small non-coding RNAs and RNA modification in the brain
LJ Leighton, TW Bredy - Non-coding RNA, 2018 - mdpi.com
Small non-coding RNAs are essential for transcription, translation and gene regulation in all
cell types, but are particularly important in neurons, with known roles in neurodevelopment, …
cell types, but are particularly important in neurons, with known roles in neurodevelopment, …
A new member in the Argonaute crew: the mt-miRNAs
A Pozzi, DK Dowling - bioRxiv, 2020 - biorxiv.org
Mutations within the mitochondrial genome have been linked to many diverse phenotypes.
Moreover, the effects of these mutations have been shown to differ across sexes and …
Moreover, the effects of these mutations have been shown to differ across sexes and …