Embryo-Like Features in Developing Bacillus subtilis Biofilms
Correspondence between evolution and development has been discussed for more than two
centuries. Recent work reveals that phylogeny−ontogeny correlations are indeed present …
centuries. Recent work reveals that phylogeny−ontogeny correlations are indeed present …
Alignment-free detection of local similarity among viral and bacterial genomes
M Domazet-Lošo, B Haubold - Bioinformatics, 2011 - academic.oup.com
… The most prevalent form of HIV is the M group of HIV-1, which is divided into eight subtypes
(A, B, C, D, F, G, H, J) based on the sequence of their 9 and 10 kb genomes. However, …
(A, B, C, D, F, G, H, J) based on the sequence of their 9 and 10 kb genomes. However, …
Efficient estimation of pairwise distances between genomes
M Domazet-Lošo, B Haubold - Bioinformatics, 2009 - academic.oup.com
Motivation: Genome comparison is central to contemporary genomics and typically relies on
sequence alignment. However, genome-wide alignments are difficult to compute. We have, …
sequence alignment. However, genome-wide alignments are difficult to compute. We have, …
[HTML][HTML] Macroevolutionary dynamics of gene family gain and loss along multicellular eukaryotic lineages
M Domazet-Lošo, T Široki, K Šimičević… - Nature …, 2024 - nature.com
The gain and loss of genes fluctuate over evolutionary time in major eukaryotic clades.
However, the full profile of these macroevolutionary trajectories is still missing. To give a more …
However, the full profile of these macroevolutionary trajectories is still missing. To give a more …
[HTML][HTML] A novel time-lapse imaging method for studying developing bacterial biofilms
In nature, bacteria prevailingly reside in the form of biofilms. These elaborately organized
surface-bound assemblages of bacterial cells show numerous features of multicellular …
surface-bound assemblages of bacterial cells show numerous features of multicellular …
[HTML][HTML] Pleomorphic Variants of Borreliella (syn. Borrelia) burgdorferi Express Evolutionary Distinct Transcriptomes
… For instance, by using the permissive criteria (Table 1) we found that 74% of genes (39
out of 53 genes in the whole genome) which are annotated with the COG term M (cell wall/…
out of 53 genes in the whole genome) which are annotated with the COG term M (cell wall/…
Alignment-free detection of horizontal gene transfer between closely related bacterial genomes
M Domazet-Lošo, B Haubold - Mobile genetic elements, 2011 - Taylor & Francis
Bacterial epidemics are often caused by strains that have acquired their increased virulence
through horizontal gene transfer. Due to this association with disease, the detection of …
through horizontal gene transfer. Due to this association with disease, the detection of …
[HTML][HTML] Gmos: rapid detection of genome mosaicism over short evolutionary distances
M Domazet-Lošo, T Domazet-Lošo - PloS one, 2016 - journals.plos.org
… gmos takes Q and S as input and computes the mosaic structure of Q, denoted M. M … i ,
i = 1,.., n, and (ii) computation of the mosaic structure of the query, M. The program returns …
i = 1,.., n, and (ii) computation of the mosaic structure of the query, M. The program returns …
An alignment-free distance measure for closely related genomes
B Haubold, M Domazet-Loso, T Wiehe - … International Workshop, RECOMB …, 2008 - Springer
Phylogeny reconstruction on a genome scale remains computationally challenging even for
closely related organisms. Here we propose an alignment-free pairwise distance measure, …
closely related organisms. Here we propose an alignment-free pairwise distance measure, …
Animals in a bacterial world, a new imperative for the life sciences
M McFall-Ngai, MG Hadfield… - Proceedings of the …, 2013 - National Acad Sciences
In the last two decades, the widespread application of genetic and genomic approaches has
revealed a bacterial world astonishing in its ubiquity and diversity. This review examines …
revealed a bacterial world astonishing in its ubiquity and diversity. This review examines …