Despite a substantial literature using life cycle assessment (LCA) approach, the extent to
which second and third generation biofuels are more sustainable than the first generation …

In recent years, efforts to improve sugarcane have focused on the development of biotechnology
for this crop. It has become clear that sugarcane lacks tools for the biotechnological …

This unit describes how to use BWA and the Genome Analysis Toolkit (GATK) to map genome
sequencing data to a reference and produce high‐quality variant calls that can be used in …

Brazil is the world’s largest producer of sugarcane and one of the leading suppliers of sugar
and ethanol worldwide. In the 2019–2020 crop season, the country produced 642.7 million …

Comprehensive disease gene discovery in both common and rare diseases will require the
efficient and accurate detection of all classes of genetic variation across tens to hundreds of …

Medulloblastomas are the most common malignant brain tumours in children 1 . Identifying
and understanding the genetic events that drive these tumours is critical for the development …

… We thank M. Sawadogo and RG Roeder for the generous gift of the piasmids p(CaAT),s and
… We are grateful to M. Yaniv (Paris) for communication of unpublished results. This work was …

Of the current next-generation sequencing technologies, SMRT sequencing is sometimes
overlooked. However, attributes such as long reads, modified base detection and high …

The evolution of gene expression in mammalian organ development remains largely
uncharacterized. Here we report the transcriptomes of seven organs (cerebrum, cerebellum, heart, …

Self-healing hydrogels use spontaneous intermolecular forces to recover from physical damage
caused by extreme strain, pressure or tearing. Such materials are of potential use in soft …