… Options include high-dose methotrexate (3-8 g/m)64,65 high-dose cytarabine (3 g/m)66,67
capecitebine (particularly for breast cancer),68-71 thiotepa,72 … Bertalan made no disclosures. …

Our knowledge of species and functional composition of the human gut microbiome is rapidly
increasing, but it is still based on very few cohorts and little is known about variation across …

To understand the impact of gut microbes on human health and well-being it is crucial to
assess their genetic potential. Here we describe the Illumina-based metagenomic sequencing, …

We are facing a global metabolic health crisis provoked by an obesity epidemic. Here we
report the human gut microbial composition in a population sample of 123 non-obese and 169 …

Diverse genetic, epigenetic, and developmental programs drive glioblastoma, an incurable
and poorly understood tumor, but their precise characterization remains challenging. Here, …

We report here the genome sequence of an ancient human. Obtained from ∼4,000-year-old
permafrost-preserved hair, the genome represents a male individual from the first known …

Copy number variants (CNVs) have been strongly implicated in the genetic etiology of
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …

Brain metastases from lung adenocarcinoma (BM-LUAD) frequently cause patient mortality.
To identify genomic alterations that promote brain metastases, we performed whole-exome …

… organisms indicates that GDI has more CDS exclusively conserved with Methylobacterium
populi BJ001 (133 genes) than with the others, which is consistent with the fact that M. populi …

An increasing fraction of patients with metastatic cancer develop leptomeningeal dissemination
of disease (LMD), and survival is dismal 1 , 2 – 3 . We conducted a single-arm, phase 2 …