Recognition of a pathogen by the plant immune system often triggers a form of regulated
cell death traditionally known as the hypersensitive response (HR). This type of cell death …

Dysregulation of signaling pathways in multiple sclerosis (MS) can be analyzed by
phosphoproteomics in peripheral blood mononuclear cells (PBMCs). We performed in vitro kinetic …

Background Networks are popular and powerful tools to describe and model biological
processes. Many computational methods have been developed to infer biological networks from …

… Contributed equally to this work with: Marti Bernardo-Faura, … Contributed equally to this work
with: Marti Bernardo-Faura, … related to either Bax or ΔΨ m . Instead, FL modeling proposes a …

Cells respond to environmental stimuli via specialized signaling pathways. Concurrent
stimuli trigger multiple pathways that integrate information, predominantly via protein …

The pathogenesis of multiple sclerosis (MS) involves alterations to multiple pathways and
processes, which represent a significant challenge for developing more-effective therapies. …

Development and fitness of any organism rely on properly controlled gene expression. This
is especially true for plants, as their development is determined by both internal and external …

Activity-based protein profiling (ABPP) is a powerful proteomic technique to display protein
activities in a proteome. It is based on the use of small molecular probes that react with the …

The majority of melanomas have been shown to harbor somatic mutations in the RAS-RAF-MEK-MAPK
and PI3K-AKT pathways, which play a major role in regulation of proliferation …

Background Multiple sclerosis (MS) is a major health problem, leading to a significant disability
and patient suffering. Although chronic activation of the immune system is a hallmark of …