All schizophrenic patients admitted consecutively either to the Psychiatric Hospital of the
University of Munich (group 1,N=183) or the Mental State Hospital Haar/Munich (group 2,N=447…

Schizophrenia has a heritability of 60–80% 1 , much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …

Polygenic risk scores have shown great promise in predicting complex disease risk and will
become more accurate as training sample sizes increase. The standard approach for …

Copy number variants (CNVs) have been strongly implicated in the genetic etiology of
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …

Regulatory and coding variants are known to be enriched with associations identified by
genome-wide association studies (GWASs) of complex disease, but their contributions to trait …

Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology.
Understanding the genetic factors contributing to the shared and disorder-specific symptoms …

A genome scan meta-a nalysis (GSMA) was carried out on 32 independent genome-wide
linkage scan analyses that included 3255 pedigrees with 7413 genotyped cases affected with …

… ,4 Margitta Borrmann-Hassenbach,5 Margot Albus,5 Bernard Lerer,6 Marcella Rietschel,2,7 …
For contribution of clinical information and blood samples, we are grateful to M. Gross, TG …

The authors exposed 10 healthy human volunteers to the stress of loud (100 dB) noise under
controllable and uncontrollable conditions on two separate days. Subjects reported higher …

Several independent studies and meta-analyses aimed at identifying genomic regions linked
to bipolar disorder (BP) have failed to find clear and consistent evidence of linkage regions…