User profiles for M. W. Klymkowsky

Michael Klymkowsky

Professor of Molecular, Cellular, and Developmental Biology, University of Colorado …
Verified email at colorado.edu
Cited by 10526

Epithelial-mesenchymal transition: a cancer researcher's conceptual friend and foe

MW Klymkowsky, P Savagner - The American journal of pathology, 2009 - Elsevier
Epithelial-mesenchymal transition (EMT) describes a series of rapid changes in cellular
phenotype. During EMT, epithelial cells down-modulate cell-cell adhesion structures, alter their …

Bioliteracy and teaching efficacy: what biologists can learn from physicists

MW Klymkowsky, K Garvin-Doxas… - Cell Biology Education, 2003 - Am Soc Cell Biol
The introduction of the Force Concept Inventory (FCI) by David Hestenes and colleagues in
1992 produced a remarkable impact within the community of physics teachers. An …

A whole-mount immunocytochemical analysis of the expression of the intermediate filament protein vimentin in Xenopus

JA Dent, AG Polson, MW Klymkowsky - Development, 1989 - journals.biologists.com
We have developed a whole-mount immunocytochemical method for Xenopus and used it
to map the expression of the intermediate filament protein vimentin during early …

[PDF][PDF] Regulation of Wnt signaling by Sox proteins: XSox17α/β and XSox3 physically interact with β-catenin

…, GD Barish, BO Williams, P Lavender, MW Klymkowsky… - Molecular cell, 1999 - cell.com
Using a functional screen in Xenopus embryos, we identified a novel function for the HMG
box protein XSox17β. Ectopic expression of XSox17β ventralizes embryos by inhibiting the …

Understanding randomness and its impact on student learning: lessons learned from building the Biology Concept Inventory (BCI)

K Garvin-Doxas, MW Klymkowsky - CBE—Life Sciences …, 2008 - Am Soc Cell Biol
While researching student assumptions for the development of the Biology Concept Inventory
(BCI; http://bioliteracy.net ), we found that a wide class of student difficulties in molecular …

Whole-mount staining of Xenopus and other vertebrates

MW Klymkowsky, J Hanken - Methods in cell biology, 1991 - Elsevier
Publisher Summary This chapter discusses whole-mount staining of xenopus and other
vertebrates. Whole-mount staining makes the analysis of normal and experimentally …

Lost in Lewis structures: An investigation of student difficulties in developing representational competence

…, SM Underwood, MW Klymkowsky - Journal of Chemical …, 2010 - ACS Publications
Because Lewis structures provide a direct connection between molecular structure and
properties, the ability to construct and use them is an integral component of many chemistry …

[PDF][PDF] Regulation of TCF3 by Wnt-dependent phosphorylation during vertebrate axis specification

H Hikasa, J Ezan, K Itoh, X Li, MW Klymkowsky… - Developmental cell, 2010 - cell.com
A commonly accepted model of Wnt/β-catenin signaling involves target gene activation by a
complex of β-catenin with a T-cell factor (TCF) family member. TCF3 is a transcriptional …

[PDF][PDF] The body language of cells: the intimate connection between cell adhesion and behavior

MW Klymkowsky, B Parr - Cell, 1995 - core.ac.uk
A simple touch between organisms can convey a wide range of different messages, from
affection to hostility. Touch appears critical for both social intercourse and the achievement of …

Development and assessment of a molecular structure and properties learning progression

…, CZ Hilley, MW Klymkowsky - Journal of Chemical …, 2012 - ACS Publications
Previously, we found that: (i) many students were unable to construct representations of
simple molecular structures; (ii) a majority of students fail to make the important connection …