User profiles for M. T. Swain

Martin Swain

Senior Lecturer in Bioinformatics, Aberystwyth University
Verified email at aber.ac.uk
Cited by 3428

Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African Trypanosomiasis

…, AK Snyder, TP Srivastava, EJ Stanley, MT Swain… - Science, 2014 - science.org
Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan
Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease …

[HTML][HTML] Direct Sequencing of Cryptosporidium in Stool Samples for Public Health

A Morris, G Robinson, MT Swain… - Frontiers in Public …, 2019 - frontiersin.org
The protozoan parasite Cryptosporidium is an important cause of diarrheal disease (cryptosporidiosis)
in humans and animals, with significant morbidity and mortality especially in …

A post-assembly genome-improvement toolkit (PAGIT) to obtain annotated genomes from contigs

MT Swain, IJ Tsai, SA Assefa, C Newbold… - Nature protocols, 2012 - nature.com
Genome projects now produce draft assemblies within weeks owing to advanced high-throughput
sequencing technologies. For milestone projects such as Escherichia coli or Homo …

Restriction and recruitment—gene duplication and the origin and evolution of snake venom toxins

AD Hargreaves, MT Swain, MJ Hegarty… - Genome biology and …, 2014 - academic.oup.com
Snake venom has been hypothesized to have originated and diversified through a process
that involves duplication of genes encoding body proteins with subsequent recruitment of the …

Protein and small non-coding RNA-enriched extracellular vesicles are released by the pathogenic blood fluke Schistosoma mansoni

FC Nowacki, MT Swain, OI Klychnikov… - Journal of …, 2015 - Taylor & Francis
Background Penetration of skin, migration through tissues and establishment of long-lived
intravascular partners require Schistosoma parasites to successfully manipulate definitive …

[HTML][HTML] De novo assembly of red clover transcriptome based on RNA-Seq data provides insight into drought response, gene discovery and marker identification

SA Yates, MT Swain, MJ Hegarty, I Chernukin, M Lowe… - BMC genomics, 2014 - Springer
Background Red clover (Trifolium pratense L.) is a versatile forage crop legume, which can
tolerate a variety of soils and is suitable for silage production for winter feed and for grazing. …

[HTML][HTML] The genetics of prey susceptibility to myxobacterial predation: A review, including an investigation into Pseudomonas aeruginosa mutations affecting …

MT Swain, JMT So, E Hoiczyk, NP Tucker… - Microbial …, 2021 - karger.com
Bacterial predation is a ubiquitous and fundamental biological process, which influences the
community composition of microbial ecosystems. Among the best characterised bacterial …

Upgrading short-read animal genome assemblies to chromosome level using comparative genomics and a universal probe set

…, A Mandawala, K Fowler, S Joseph, MT Swain… - Genome …, 2017 - genome.cshlp.org
Most recent initiatives to sequence and assemble new species’ genomes de novo fail to
achieve the ultimate endpoint to produce contigs, each representing one whole chromosome. …

Evolutionary genomics of anthroponosis in Cryptosporidium

…, TC Mathers, BJ Ward, JA Pachebat, MT Swain… - Nature …, 2019 - nature.com
Human cryptosporidiosis is the leading protozoan cause of diarrhoeal mortality worldwide,
and a preponderance of infections is caused by Cryptosporidium hominis and C. parvum. …

[HTML][HTML] Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes

…, G Savini, L Schoofs, F Scolari, MT Swain… - Genome biology, 2019 - Springer
Background Tsetse flies (Glossina sp.) are the vectors of human and animal trypanosomiasis
throughout sub-Saharan Africa. Tsetse flies are distinguished from other Diptera by unique …