▪ Abstract Autoimmunity is a complex process that likely results from the summation of
multiple defective tolerance mechanisms. The NOD mouse strain is an excellent model of …

Autoimmune Polyendocrine Syndromes Autoimmune polyendocrine syndromes comprise a
diverse group of clinical entities involving functional impairment of multiple endocrine …

… ANDERSON is associate professor of higher education at the University of Minnesota. Her
current re sea rch includes the Academic Life Project (an NSF-funded longitudinal study of …

Humans expressing a defective form of the transcription factor AIRE (autoimmune regulator)
develop multiorgan autoimmune disease. We used aire- deficient mice to test the …

… disease in a mouse model of MS, and anti-EBNA1 and … MS. Our results provide a mechanistic
link for the association between MS and EBV and could guide the development of new MS …

… Anderson … Anderson and Raymond de Vries. … Attempts to foster integrity that focus
only on FFP therefore miss a great deal. We assume that our reliance on self reports of …

Though international relations and the rise and fall of European states are widely studied,
little is available to students and non-specialists on the origins, development and operation of …

Aire promotes the tolerization of thymocytes by inducing the expression of a battery of
peripheral-tissue antigens in thymic medullary epithelial cells. We demonstrate that the cellular …

Objectives. —To identify the prevalence and determinants of data-withholding behaviors
among academic life scientists. Design. —Mailed survey of 3394 life science faculty in the 50 …

Disclosures: PD Burbelo reported US Patent no. 10,564,152 issued. JC Casanova reported
a patent to 63/055,155 pending and a patent to 63/141,669 pending. No other disclosures …