The ability of cells to adhere to each other and to their surrounding extracellular matrices is
essential for a multicellular existence. Adhesion provides physical support for cells, regulates …

The formation, maturation, and dissolution of focal adhesions are basic prerequisites of cell
migration and rely on the recruitment, signalling, and endocytosis of integrins. In many …

One aspirational goal of computational chemistry is to predict potent and drug-like binders
for any protein, such that only those that bind are synthesized. In this Roadmap, we describe …

Routine full characterization of Mycobacterium tuberculosis is culture based, taking many
weeks. Whole-genome sequencing (WGS) can generate antibiotic susceptibility profiles to …

Cell migration in wound healing and disease is critically dependent on integration with the
extracellular matrix, but the receptors that couple matrix topography to migratory behavior …

Biodiesels (fatty acid methyl esters) derived from oleaginous microbes (microalgae, yeast,
and bacteria) are being actively pursued as potential renewable substitutes for petroleum …

Cell migration during wound healing requires adhesion receptor turnover to enable the
formation and disassembly of cell-extracellular matrix contacts. Although recent advances have …

Precise spatiotemporal coordination of integrin adhesion complex dynamics is essential for
efficient cell migration. For cells adherent to fibronectin, differential engagement of α 5 β 1 …

The fibronectin receptors α 5 β 1 integrin and syndecan-4 cocluster in focal adhesions and
coordinate cell migration by making individual contributions to the suppression of RhoA …

An extensive database of stress concentrations and degree of bending in tubular K-joints
under balanced axial loading, generated recently in a finite element parametric study, has …