G-protein-coupled receptors or GPCRs have been a major area of study in the past decades.
This is not surprising as this group, comprising a thousand-odd proteins, constitutes the …

… Cells were grown to 65–70% confluency in 35-mm dishes and transfected with 2 μg of
SR2-GFP DNA by using 10 μg of lipofectamine in 1 ml of OptiMEM. After 2 days in culture, cells …

… Bertaccini: investigation; ES Monuki: formal analysis and significant editing of manuscript;
MM Panicker: conceptualization, formal analysis, and visualization; MM Pathak: …

… Our calculations estimated the puncta to contain serotonin at concentrations ranging from
a minimum of 89 mM to a maximum of 442 mM. However, it is important to note that this value …

Aim Severe mental illnesses (SMI), such as bipolar disorder and schizophrenia, are highly
heritable, and have a complex pattern of inheritance. Genome‐wide association studies …

… The SB1 cells, grown in 35-mm coverslip dishes, were serum starved for 24 hours and treated
with cycloheximide (100 μg/ml) to clear the internal fluorescence, as already mentioned in …

… treated with 200 μl of ascorbate buffer (pH 4.5) (140 mM sodium ascorbate/65 mM ascorbic
acid/1 mM CaCl 2 /1 mM MgCl 2 ) for 10 min to remove membrane-bound noninternalized …

Background There is emerging evidence that there are shared genetic, environmental and
developmental risk factors in psychiatry, that cut across traditional diagnostic boundaries. …

… of 25 mM Tris-hydrochloride (pH 8.4)-192 mM glycine-20% methanol. The nitrocellulose
sheet was washed with distilled water and then incubated for 1 h with 50 ml of 3% bovine serum …

The serotonergic system has been implicated in emotional and cognitive function. In
particular, 5-HT2A (5-hydroxytrytamine receptor 2A) is attributed to a number of disorders like …