Genetic clustering algorithms require a certain amount of data to produce informative results.
In the common situation that individuals are sampled at several locations, we show how …

Methods for detecting nucleotide substitution rates that are faster or slower than expected
under neutral drift are widely used to identify candidate functional elements in genomic …

The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from
the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and …

Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

Human accelerated regions (HARs) are DNA sequences that changed very little throughout
mammalian evolution, but then experienced a burst of changes in humans since divergence …

The comparison of related genomes has emerged as a powerful lens for genome interpretation.
Here we report the sequencing and comparative analysis of 29 eutherian genomes. We …

Since the divergence of humans and chimpanzees about 5 million years ago, these species
have undergone a remarkable evolution with drastic divergence in anatomy and cognitive …

Detecting selective sweeps from genomic SNP data is complicated by the intricate ascertainment
schemes used to discover SNPs, and by the confounding influence of the underlying …

Whole-genome sequences provide a rich source of information about human evolution.
Here we describe an effort to estimate key evolutionary parameters based on the whole-genome …

Genome-wide scans for positively selected genes (PSGs) in mammals have provided insight
into the dynamics of genome evolution, the genetic basis of differences between species, …