Myelin, myelin-related disorders, and psychosis

MI Mighdoll, R Tao, JE Kleinman, TM Hyde - Schizophrenia research, 2015 - Elsevier
The neuropathological basis of schizophrenia and related psychoses remains elusive despite
intensive scientific investigation. Symptoms of psychosis have been reported in a number …

Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and …

…, JH Callicott, LR Testa, MI Mighdoll… - Journal of …, 2014 - Soc Neuroscience
Early in development, GABA, an inhibitory neurotransmitter in adults, is excitatory. NKCC1 (SLC12A2)
encodes one of two cation chloride cotransporters mediating the conversion of …

[HTML][HTML] Deficits in the activity of presynaptic γ-aminobutyric acid type B receptors contribute to altered neuronal excitability in fragile X syndrome

JY Kang, J Chadchankar, TN Vien, MI Mighdoll… - Journal of Biological …, 2017 - ASBMB
The behavioral and anatomical deficits seen in fragile X syndrome (FXS) are widely
believed to result from imbalances in the relative strengths of excitatory and inhibitory …

Genetic risk mechanisms of posttraumatic stress disorder in the human brain

…, AL Goldman, MI Mighdoll… - Journal of …, 2018 - Wiley Online Library
Posttraumatic stress disorder (PTSD) follows exposure to a traumatic event in susceptible
individuals. Recently, genome‐wide association studies have identified a number of genetic …

[HTML][HTML] Strong components of epigenetic memory in cultured human fibroblasts related to site of origin and donor age

…, R Tao, JG Chenoweth, A Brandtjen, MI Mighdoll… - PLoS …, 2016 - journals.plos.org
Differentiating pluripotent cells from fibroblast progenitors is a potentially transformative tool
in personalized medicine. We previously identified relatively greater success culturing dura-…

Brain donation at autopsy: clinical characterization and toxicologic analyses

MI Mighdoll, TM Hyde - Handbook of Clinical Neurology, 2018 - Elsevier
The study of postmortem human brain tissue is central to the advancement of neurobiologic
studies of psychiatric and neurologic illnesses, particularly the study of brain-specific …

Implementation and clinical characteristics of a posttraumatic stress disorder brain collection

MI Mighdoll, A Deep‐Soboslay… - Journal of …, 2018 - Wiley Online Library
Mighdoll and Amy Deep-Soboslay drafted the manuscript with input from all coauthors. Joel
Mighdoll consented and collected clinical information on all brains in this study. Thomas M. …

[HTML][HTML] African-American and Caucasian participation in postmortem human brain donation for neuropsychiatric research

A Deep-Soboslay, MI Mighdoll, AE Jaffe, SB Thomas… - Plos one, 2019 - journals.plos.org
Increased African-American research participation is critical to the applicability and
generalizability of biomedical research, as population diversity continues to increase both …

Preliminary power train design for a state-of-the-art electric vehicle

P Mighdoll, WF Hahn - 1978 - ntrs.nasa.gov
… Phillip Mighdoll and William F. Hahn Design and Development Division … Mighdoll was the
project engineer and Dr. Hahn was the program manager… 0-70124 sat., 30 mi, and hydraulic …

[BOOK][B] Brain banking

I Huitinga, MJ Webster - 2018 - books.google.com
MI Mighdoll Lieber Institute for Brain Development, Johns Hopkins University School of …
Brain donation at autopsy: clinical characterization and toxicologic analyses MI Mighdoll and TM …