User profiles for M. H. Ellisman

Mark Ellisman

Professor of Neurosciences and Bioengineering, UCSD
Verified email at ucsd.edu
Cited by 75980

The fluorescent toolbox for assessing protein location and function

BNG Giepmans, SR Adams, MH Ellisman, RY Tsien - science, 2006 - science.org
Advances in molecular biology, organic chemistry, and materials science have recently created
several new classes of fluorescent probes for imaging in cell biology. Here we review the …

Nerve regeneration through artificial tubular implants

…, JM Le Beau, FM Longo, MH Ellisman - Progress in neurobiology, 1989 - Elsevier
2.2. 1. Surgical procedure 2.2. 2. Materials for use as tubes 2.2. 2. I. Materials of biological
origin 2.2. 2, 2. Metal 2.2. 2, 3. Millipore 2.2. 2, 4. Silicone rubber and plastics 2.2. 2.5. Semi-…

[PDF][PDF] Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet

…, A Chaix, M Joens, JAJ Fitzpatrick, MH Ellisman… - Cell metabolism, 2012 - cell.com
While diet-induced obesity has been exclusively attributed to increased caloric intake from
fat, animals fed a high-fat diet (HFD) ad libitum (ad lib) eat frequently throughout day and night…

[HTML][HTML] Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

T Kuwana, MR Mackey, G Perkins, MH Ellisman… - Cell, 2002 - cell.com
Bcl-2 family proteins regulate the release of proteins like cytochrome c from mitochondria
during apoptosis. We used cell-free systems and ultimately a vesicular reconstitution from …

Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains

…, ME Martone, YZ Jones, MH Ellisman - Journal of …, 2002 - Soc Neuroscience
Protoplasmic astrocytes are increasingly thought to interact extensively with neuronal elements
in the brain and to influence their activity. Recent reports have also begun to suggest that …

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

…, Y Yu, J Roos, JA Kozak, TJ Deerinck, MH Ellisman… - Nature, 2005 - nature.com
As the sole Ca 2+ entry mechanism in a variety of non-excitable cells, store-operated calcium
(SOC) influx is important in Ca 2+ signalling and many other cellular processes 1 , 2 , 3 . A …

Design and synthesis of a minimal bacterial genome

…, N Assad-Garcia, TJ Deerinck, MH Ellisman… - Science, 2016 - science.org
INTRODUCTION In 1984, the simplest cells capable of autonomous growth, the mycoplasmas,
were proposed as models for understanding the basic principles of life. In 1995, we …

Multicolor and electron microscopic imaging of connexin trafficking

…, DW Laird, GE Sosinsky, RY Tsien, MH Ellisman - Science, 2002 - science.org
Recombinant proteins containing tetracysteine tags can be successively labeled in living
cells with different colors of biarsenical fluorophores so that older and younger protein …

Directed evolution of APEX2 for electron microscopy and proximity labeling

…, JD Martell, KJ Kamer, TJ Deerinck, MH Ellisman… - Nature …, 2015 - nature.com
APEX is an engineered peroxidase that functions as an electron microscopy tag and a
promiscuous labeling enzyme for live-cell proteomics. Because limited sensitivity precludes …

[HTML][HTML] A genetically encoded tag for correlated light and electron microscopy of intact cells, tissues, and organisms

…, EB Ramko, MW Davidson, Y Jin, MH Ellisman… - PLoS …, 2011 - journals.plos.org
Electron microscopy (EM) achieves the highest spatial resolution in protein localization, but
specific protein EM labeling has lacked generally applicable genetically encoded tags for in …