User profiles for M. G. Behringer

Megan Behringer

Vanderbilt University
Verified email at vanderbilt.edu
Cited by 645

[HTML][HTML] Rapid evolution of mutation rate and spectrum in response to environmental and population-genetic challenges

W Wei, WC Ho, MG Behringer, SF Miller… - Nature …, 2022 - nature.com
Ecological and demographic factors can significantly shape the evolution of microbial populations
both directly and indirectly, as when changes in the effective population size affect the …

Microbial population dynamics and evolutionary outcomes under extreme energy limitation

…, ME Muscarella, MG Behringer… - Proceedings of the …, 2021 - National Acad Sciences
Microorganisms commonly inhabit energy-limited ecosystems where cellular maintenance
and reproduction is highly constrained. To gain insight into how individuals persist under …

Escherichia coli cultures maintain stable subpopulation structure during long-term evolution

MG Behringer, BI Choi, SF Miller… - Proceedings of the …, 2018 - National Acad Sciences
How genetic variation is generated and maintained remains a central question in evolutionary
biology. When presented with a complex environment, microbes can take advantage of …

Genome-Wide Estimates of Mutation Rates and Spectrum in Schizosaccharomyces pombe Indicate CpG Sites are Highly Mutagenic Despite the Absence of DNA …

MG Behringer, DW Hall - G3: Genes, Genomes, Genetics, 2016 - academic.oup.com
… cerevisiae is problematic (MG Behringer, unpublished data) due to their repetitive nature,
so mutations in these genes may have been missed in that study. In addition, given our …

The repeatability of genome-wide mutation rate and spectrum estimates

MG Behringer, DW Hall - Current genetics, 2016 - Springer
Over the last decade, mutation studies have grown in popularity due to the affordability and
accessibility of whole genome sequencing. As the number of species in which spontaneous …

Similar mutation rates but highly diverse mutation spectra in ascomycete and basidiomycete yeasts

H Long, MG Behringer, E Williams… - Genome Biology and …, 2016 - academic.oup.com
Yeast species are extremely diverse and not monophyletic. Because the majority of yeast
research focuses on ascomycetes, the mutational determinants of genetic diversity across …

[HTML][HTML] Case studies in the assessment of microbial fitness: seemingly subtle changes can have major effects on phenotypic outcomes

SB Worthan, RDP McCarthy, MG Behringer - Journal of Molecular …, 2023 - Springer
Following the completion of an adaptive evolution experiment, fitness evaluations are
routinely conducted to assess the magnitude of adaptation. In doing so, proper consideration …

Enhanced nutrient uptake is sufficient to drive emergent cross-feeding between bacteria in a synthetic community

RK Fritts, JT Bird, MG Behringer, A Lipzen… - The ISME …, 2020 - academic.oup.com
Interactive microbial communities are ubiquitous, influencing biogeochemical cycles and
host health. One widespread interaction is nutrient exchange, or cross-feeding, wherein …

Complex ecotype dynamics evolve in response to fluctuating resources

MG Behringer, WC Ho, JC Meraz, SF Miller, GF Boyer… - Mbio, 2022 - Am Soc Microbiol
Ecotypic diversification and its associated cooperative behaviors are frequently observed in
natural microbial populations whose access to resources is often sporadic. However, the …

Bacterial adenine cross-feeding stems from a purine salvage bottleneck

YC Chuang, NW Haas, R Pepin, MG Behringer… - The ISME …, 2024 - academic.oup.com
Diverse ecosystems host microbial relationships that are stabilized by nutrient cross-feeding.
Cross-feeding can involve metabolites that should hold value for the producer. …