Langerhans cells (LCs) reside in the epidermis as a dense network of immune system
sentinels. These cells determine the appropriate adaptive immune response (inflammation or …

… Pollack was previously professor of computer science and professor and director of the …
A Fellow of the AAAI, Pollack recently completed a term as editor-in-chief of the Journal of …

Monoclonal antibody (mAb) drugs that stimulate antitumor immunity are transforming cancer
treatment but require optimization for maximum clinical impact. Here, we show that, unlike …

Mycobacterium tuberculosis (Mtb) causes the human disease tuberculosis (TB) and remains
the top global infectious pandemic after coronavirus disease 2019 (COVID-19). Furthermore…

Cutaneous melanoma is highly immunogenic, yet primary melanomas and metastases
develop successfully in otherwise immunocompetent patients. To investigate the local …

An architecture for a rational agent must allow for means‐end reasoning, for the weighing of
competing alternatives, and for interactions betwen these two forms of reasoning. Such an …

Allergen-specific responses in atopic dermatitis (AD) are skewed toward a Th2 profile.
However, individuals with AD have been shown to make effective virus-specific Th1 responses, …

BACKGROUND Matrix metalloproteinases (MMPs) are key regulators of tissue destruction
in tuberculosis (TB) and may be targets for host-directed therapy. We conducted a phase II …

… My close advisors on matters of artificial intelligence-David Israel and Martha Pollack-have
taught me that this is also the paradigm that dominates there as well, in the guise of the "…

Purpose: Cutaneous squamous cell carcinoma (cSCC) is the most common human cancer
with metastatic potential. Despite T cells accumulating around cSCCs, these tumors continue …