Prevalence, incidence and mortality of type 1 and type 2 diabetes in Denmark 1996–2016
B Carstensen, PF Rønn, ME Jørgensen - BMJ Open Diabetes …, 2020 - drc.bmj.com
Introduction The objective of this study was to give an overview of prevalence, incidence and
mortality of type 1 (T1D) and type 2 diabetes (T2D) in Denmark, and their temporal trends. …
mortality of type 1 (T1D) and type 2 diabetes (T2D) in Denmark, and their temporal trends. …
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
…, MA Ikram, M Ingelsson, ME Jørgensen, T Jørgensen… - Nature …, 2018 - nature.com
We expanded GWAS discovery for type 2 diabetes (T2D) by combining data from 898,130
European-descent individuals (9% cases), after imputation to high-density reference panels. …
European-descent individuals (9% cases), after imputation to high-density reference panels. …
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
…, F Jasmine, G Jiang, JB Jonas, ME Jørgensen - Nature …, 2022 - nature.com
We assembled an ancestrally diverse collection of genome-wide association studies (GWAS)
of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non…
of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non…
Transport of defense compounds from source to sink: lessons learned from glucosinolates
Plants synthesize a plethora of defense compounds crucial for their survival in a challenging
and changing environment. Transport processes are important for shaping the distribution …
and changing environment. Transport processes are important for shaping the distribution …
The Danish adult diabetes registry
ME Jørgensen, JK Kristensen… - Clinical …, 2016 - Taylor & Francis
Aim of the database The aim of the Danish Adult Diabetes Registry (DADR) is to provide data
from both the primary health care sector (general practice [GP]) and the secondary sector (…
from both the primary health care sector (general practice [GP]) and the secondary sector (…
An expanded genome-wide association study of type 2 diabetes in Europeans
To characterize type 2 diabetes (T2D)-associated variation across the allele frequency spectrum,
we conducted a meta-analysis of genome-wide association data from 26,676 T2D case …
we conducted a meta-analysis of genome-wide association data from 26,676 T2D case …
Lower risk of heart failure and death in patients initiated on sodium-glucose cotransporter-2 inhibitors versus other glucose-lowering drugs: the CVD-REAL study …
… Dr Jørgensen is a shareholder of Novo Nordisk, was employed by Steno Diabetes Center
A/S until December 31, 2016, a research hospital working in the Danish National Health …
A/S until December 31, 2016, a research hospital working in the Danish National Health …
Exome-wide association study of plasma lipids in> 300,000 individuals
…, MR Jarvelin, GB Jensen, ME Jørgensen… - Nature …, 2017 - nature.com
We screened variants on an exome-focused genotyping array in> 300,000 participants (replication
in> 280,000 participants) and identified 444 independent variants in 250 loci …
in> 280,000 participants) and identified 444 independent variants in 250 loci …
Greenlandic Inuit show genetic signatures of diet and climate adaptation
The indigenous people of Greenland, the Inuit, have lived for a long time in the extreme
conditions of the Arctic, including low annual temperatures, and with a specialized diet rich in …
conditions of the Arctic, including low annual temperatures, and with a specialized diet rich in …
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
…, B Isomaa, S Johansson, T Jørgensen, ME Jørgensen… - Nature …, 2014 - nature.com
Loss-of-function mutations protective against human disease provide in vivo validation of
therapeutic targets 1 , 2 , 3 , but none have yet been described for type 2 diabetes (T2D). …
therapeutic targets 1 , 2 , 3 , but none have yet been described for type 2 diabetes (T2D). …