Compared to conventional photon-based external beam radiation (PhXRT), carbon ion
radiotherapy (CIRT) has superior dose distribution, higher linear energy transfer (LET), and a …

The clinical success of immune checkpoint inhibitors in treating metastatic and refractory
cancers has generated significant interest in investigating their role in treating locally advanced …

Nonhomologous end-joining (NHEJ) is the predominant pathway that repairs DNA double-strand
breaks (DSBs) in mammalian cells. The DNA-dependent protein kinase (DNA-PK), …

Small extracellular vesicles (EVs) play a significant role in intercellular communication through
their non-coding RNA (ncRNA) cargo. While the initial examination of EV cargo identified …

Purpose: Current classification of head and neck squamous cell carcinomas (HNSCC) based
on anatomic site and stage fails to capture biologic heterogeneity or adequately inform …

… Story4 Department of Experimental Radiotherapy, MD Anderson Cancer Center, University
… Story, MD, EA Mendoza, RE Meyn, and J. Tofilon 1994. Pulsed-field gel electrophoretic …

Non–small cell lung cancers (NSCLCs) bearing mutations in the tyrosine kinase domain (TKD)
of the epidermal growth factor receptor (EGFR) often exhibit dramatic sensitivity to the …

Asaithamby, A., Uematsu, N., Chatterjee, A., Story, MD, Burma, S. and Chen, DJ Repair of
HZE-Particle-Induced DNA Double-Strand Breaks in Normal Human Fibroblasts. Radiat. Res. …

… Ninety-six patients treated at the MD Anderson Cancer Center for HNSCC through surgical
resection and postoperative radiotherapy comprised an independent validation set for the …

Most accelerator-based space radiation experiments have been performed with single ion
beams at fixed energies. However, the space radiation environment consists of a wide variety …