Much work has been done to identify susceptibility genes in schizophrenia and bipolar
disorder. Several well established linkages have emerged in schizophrenia. Strongly supported …

It has been conventional for psychiatric research, including the search for predisposing
genes, to proceed under the assumption that schizophrenia and bipolar disorder are separate …

… O’Donovan in 2015. Multiple drug companies work with the Psychiatric Genomics Consortium
in a manner equivalent to that of academic investigators. The other authors report no …

… The independent target samples were the MGS European-American (MGS-EA), the MGS
African-American (MGS-AA) and the UK sample described previously by O’Donovan et al 3 . …

Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of
alleles, including common alleles of small effect that might be detected by genome-wide …

The Huntington's disease (HD) gene has been mapped in 4p16.3 but has eluded identification.
We have used haplotype analysis of linkage disequilibrium to spotlight a small segment …

Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous
studies; however, a large portion of the genetic risk for this disease remains unexplained. …

Inherited alleles account for most of the genetic risk for schizophrenia. However, new (de
novo) mutations, in the form of large chromosomal copy number changes, occur in a small …

Schizophrenia is a debilitating psychiatric condition often associated with poor quality of life
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …

Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to
siblings of probands. Replication has been inconsistent for reports of significant genetic …