User profiles for M. C. Munder

Matthias Munder

Max Planck Institute of Molecular Cell Biology and Genetics, Dresden
Verified email at mpi-cbg.de
Cited by 1435

Harnessing the power of yeast to unravel the molecular basis of neurodegeneration

S Tenreiro, MC Munder, S Alberti… - Journal of …, 2013 - Wiley Online Library
Several neurodegenerative diseases, such as Parkinson's disease ( PD ), Alzheimer's disease
( AD ), Huntington's disease ( HD ), amyotrophic lateral sclerosis ( ALS ), or prion diseases…

A pH-driven transition of the cytoplasm from a fluid-to a solid-like state promotes entry into dormancy

MC Munder, D Midtvedt, T Franzmann, E Nuske, O Otto… - elife, 2016 - elifesciences.org
10.7554/eLife.09347.001 Cells can enter into a dormant state when faced with unfavorable
conditions. However, how cells enter into and recover from this state is still poorly understood…

Filament formation by metabolic enzymes is a specific adaptation to an advanced state of cellular starvation

I Petrovska, E Nüske, MC Munder, G Kulasegaran… - elife, 2014 - elifesciences.org
10.7554/eLife.02409.001 One of the key questions in biology is how the metabolism of a
cell responds to changes in the environment. In budding yeast, starvation causes a drop in …

Molecular chaperones and stress-inducible protein-sorting factors coordinate the spatiotemporal distribution of protein aggregates

L Malinovska, S Kroschwald, MC Munder… - Molecular biology of …, 2012 - Am Soc Cell Biol
Acute stress causes a rapid redistribution of protein quality control components and
aggregation-prone proteins to diverse subcellular compartments. How these remarkable changes …

[PDF][PDF] Different material states of Pub1 condensates define distinct modes of stress adaptation and recovery

S Kroschwald, MC Munder, S Maharana… - Cell reports, 2018 - cell.com
How cells adapt to varying environmental conditions is largely unknown. Here, we show that,
in budding yeast, the RNA-binding and stress granule protein Pub1 has an intrinsic …

A rapid, modular and marker-free chloroplast expression system for the green alga Chlamydomonas reinhardtii

I Bertalan, MC Munder, C Weiß, J Kopf, D Fischer… - Journal of …, 2015 - Elsevier
In search of alternative expression platforms heterologous protein production in microalgae
has gained increasing importance in the last years. Particularly, the chloroplast of the green …

Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3): a double-blind, randomised, placebo-controlled phase 3 trial

…, I Blau, A Schieferdecker, V Teleanu, M Munder… - The Lancet, 2019 - thelancet.com
Background Maintenance therapy following autologous stem cell transplantation (ASCT)
can delay disease progression and prolong survival in patients with multiple myeloma. …

Health‐related quality of life maintained over time in patients with relapsed or refractory multiple myeloma treated with daratumumab in combination with bortezomib …

…, T Masszi, I Spicka, M Munder… - British Journal of …, 2021 - Wiley Online Library
In the phase III CASTOR trial, daratumumab, bortezomib and dexamethasone (D‐Vd)
significantly extended progression‐free survival compared with bortezomib and dexamethasone (…

The essential role of SepF in mycobacterial division

S Gola, T Munder, S Casonato… - Molecular …, 2015 - Wiley Online Library
… smegmatis mc 2 155 and Corynebacterium glutamicum ATCC 13032 chromosomes and
produced as fusions to the GAL4 activation domain (AD) in pGADT7 to serve as prey. Rv2050 …

Addition of elotuzumab to lenalidomide and dexamethasone for patients with newly diagnosed, transplantation ineligible multiple myeloma (ELOQUENT-1): an open …

…, HA Dürk, A Kerkhoff, M Kropff, M Munder… - The Lancet …, 2022 - thelancet.com
Background Elotuzumab plus lenalidomide and dexamethasone has shown improved
progression-free and overall survival versus lenalidomide and dexamethasone in patients with …