BackgroundThe relative invasiveness rates (attack rates) of Streptococcus pneumoniae of
different capsular serotypes in children are not known. Estimates of capsular serotype …

Multilocus sequence typing (MLST) is a recently developed nucleotide sequence-based
method for the definitive assignment of isolates within bacterial populations to specific clones. …

Much remains unknown of the phylogeny and evolution of Mycobacterium tuberculosis, an
organism that kills 2 million people annually. Using a population-based approach that …

Whole genome sequence (WGS) data are increasingly used to characterise bacterial
pathogens. These data provide detailed information on the genotypes and likely phenotypes of …

Many host-adapted bacterial pathogens contain DNA methyltransferases (mod genes) that
are subject to phase-variable expression (high-frequency reversible ON/OFF switching of …

The extent to which recombination disrupts the bifurcating treelike phylogeny and clonal
structure imposed by binary fission on bacterial populations remains contentious. Here, we …

The genetic relatedness and evolutionary relationships between group B streptococcus (GBS)
isolates from humans and those from bovines were investigated by phylogenetic analysis …

The recent emergence of the human-pathogenic Vibrio vulnificus in Israel was investigated
by using multilocus genotype data and modern molecular evolutionary analysis tools. We …

Antimicrobial resistance is a major public health concern. Carbapenemase-producing
Enterobacterales (CPE) represent a significant health threat as some strains are resistant to …

Streptococcus pneumoniae causes substantial mortality among children under 5-years-old
worldwide. Polysaccharide conjugate vaccines (PCVs) are highly effective at reducing …