Using biomarkers to select the most at-risk population, to detect the disease while
measurable and yet not clinically apparent has been the goal of many investigations. Recent …

Importance Positron emission tomography (PET) combined with fludeoxyglucose F 18 (FDG)
is recommended for the noninvasive diagnosis of pulmonary nodules suspicious for lung …

Lung cancer is the leading cause of cancer mortality in the United States. Certain groups are
at increased risk of developing lung cancer and experience greater morbidity and mortality …

In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide
association studies, we observed large chromosomal abnormalities in a subset of clones in …

Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …

Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

Genome-wide association studies (GWAS) have identified 36 loci associated with body mass
index (BMI), predominantly in populations of European ancestry. We conducted a meta-…

Recombination, together with mutation, gives rise to genetic variation in populations. Here we
leverage the recent mixture of people of African and European ancestry in the Americas to …

Background Self-identified race or ethnic group is used to determine normal reference standards
in the prediction of pulmonary function. We conducted a study to determine whether the …

Background: There are well-documented disparities in lung cancer outcomes across populations.
Lung cancer screening (LCS) has the potential to reduce lung cancer mortality, but for …