User profiles for M. A. Swertz
Morris SwertzFull Professor / Head of Genomics Coordination Center, Dept of Genetics, University … Verified email at rug.nl Cited by 46944 |
Mutation update on the CHD7 gene involved in CHARGE syndrome
CHD7 is a member of the chromodomain helicase DNA‐binding (CHD) protein family that
plays a role in transcription regulation by chromatin remodeling. Loss‐of‐function mutations in …
plays a role in transcription regulation by chromatin remodeling. Loss‐of‐function mutations in …
[HTML][HTML] The FAIR Guiding Principles for scientific data management and stewardship
There is an urgent need to improve the infrastructure supporting the reuse of scholarly data.
A diverse set of stakeholders—representing academia, industry, funding agencies, and …
A diverse set of stakeholders—representing academia, industry, funding agencies, and …
Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
Deep sequencing of the gut microbiomes of 1135 participants from a Dutch population-based
cohort shows relations between the microbiome and 126 exogenous and intrinsic host …
cohort shows relations between the microbiome and 126 exogenous and intrinsic host …
Environmental factors shaping the gut microbiome in a Dutch population
The gut microbiome is associated with diverse diseases 1 , 2 – 3 , but a universal signature
of a healthy or unhealthy microbiome has not been identified, and there is a need to …
of a healthy or unhealthy microbiome has not been identified, and there is a need to …
Leveraging European infrastructures to access 1 million human genomes by 2022
Human genomics is undergoing a step change from being a predominantly research-driven
activity to one driven through health care as many countries in Europe now have nascent …
activity to one driven through health care as many countries in Europe now have nascent …
Cohort Profile: LifeLines, a three-generation cohort study and biobank
S Scholtens, N Smidt, MA Swertz… - International journal …, 2015 - academic.oup.com
The LifeLines Cohort Study is a large population-based cohort study and biobank that was
established as a resource for research on complex interactions between environmental, …
established as a resource for research on complex interactions between environmental, …
The effect of host genetics on the gut microbiome
The gut microbiome is affected by multiple factors, including genetics. In this study, we
assessed the influence of host genetics on microbial species, pathways and gene ontology …
assessed the influence of host genetics on microbial species, pathways and gene ontology …
[HTML][HTML] The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies
…, C Schwienbacher, ML Tammesoo, MA Swertz… - BMC endocrine …, 2014 - Springer
Background Not all obese subjects have an adverse metabolic profile predisposing them to
developing type 2 diabetes or cardiovascular disease. The BioSHaRE-EU Healthy Obese …
developing type 2 diabetes or cardiovascular disease. The BioSHaRE-EU Healthy Obese …
Neurodegenerative diseases: lessons from genome‐wide screens in small model organisms
Various age‐related neurodegenerative diseases, including Parkinson's disease, polyglutamine
expansion diseases and Alzheimer's disease, are associated with the accumulation of …
expansion diseases and Alzheimer's disease, are associated with the accumulation of …
The FAIR Guiding Principles for scientific data management and stewardship. Sci Data 3: 160018
Sometimes, experts in one field use terms not shared by others, or there may be disagreement
about which vocabulary is best suited for a specific aspect of research. As a result, it can …
about which vocabulary is best suited for a specific aspect of research. As a result, it can …