User profiles for M. A. Swertz

Morris Swertz

Full Professor / Head of Genomics Coordination Center, Dept of Genetics, University …
Verified email at rug.nl
Cited by 46944

Mutation update on the CHD7 gene involved in CHARGE syndrome

N Janssen, JEH Bergman, MA Swertz… - Human …, 2012 - Wiley Online Library
CHD7 is a member of the chromodomain helicase DNA‐binding (CHD) protein family that
plays a role in transcription regulation by chromatin remodeling. Loss‐of‐function mutations in …

[HTML][HTML] The FAIR Guiding Principles for scientific data management and stewardship

…, E Schultes, T Sengstag, T Slater, G Strawn, MA Swertz… - Scientific data, 2016 - nature.com
There is an urgent need to improve the infrastructure supporting the reuse of scholarly data.
A diverse set of stakeholders—representing academia, industry, funding agencies, and …

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

…, M Joossens, MC Cenit, P Deelen, MA Swertz… - Science, 2016 - science.org
Deep sequencing of the gut microbiomes of 1135 participants from a Dutch population-based
cohort shows relations between the microbiome and 126 exogenous and intrinsic host …

Environmental factors shaping the gut microbiome in a Dutch population

…, VC Lenters, JR Björk, JC Swarte, MA Swertz… - Nature, 2022 - nature.com
The gut microbiome is associated with diverse diseases 1 , 2 – 3 , but a universal signature
of a healthy or unhealthy microbiome has not been identified, and there is a need to …

Leveraging European infrastructures to access 1 million human genomes by 2022

…, D Salgado, E Steinfelder, MA Swertz… - Nature Reviews …, 2019 - nature.com
Human genomics is undergoing a step change from being a predominantly research-driven
activity to one driven through health care as many countries in Europe now have nascent …

Cohort Profile: LifeLines, a three-generation cohort study and biobank

S Scholtens, N Smidt, MA Swertz… - International journal …, 2015 - academic.oup.com
The LifeLines Cohort Study is a large population-based cohort study and biobank that was
established as a resource for research on complex interactions between environmental, …

The effect of host genetics on the gut microbiome

…, M Oosting, MC Cenit, AAM Masclee, MA Swertz… - Nature …, 2016 - nature.com
The gut microbiome is affected by multiple factors, including genetics. In this study, we
assessed the influence of host genetics on microbial species, pathways and gene ontology …

[HTML][HTML] The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies

…, C Schwienbacher, ML Tammesoo, MA Swertz… - BMC endocrine …, 2014 - Springer
Background Not all obese subjects have an adverse metabolic profile predisposing them to
developing type 2 diabetes or cardiovascular disease. The BioSHaRE-EU Healthy Obese …

Neurodegenerative diseases: lessons from genome‐wide screens in small model organisms

TJ Van Ham, R Breitling, MA Swertz… - EMBO molecular …, 2009 - embopress.org
Various age‐related neurodegenerative diseases, including Parkinson's disease, polyglutamine
expansion diseases and Alzheimer's disease, are associated with the accumulation of …

The FAIR Guiding Principles for scientific data management and stewardship. Sci Data 3: 160018

…, E Schultes, T Sengstag, T Slater, G Strawn, MA Swertz… - 2016 - factor.niehs.nih.gov
Sometimes, experts in one field use terms not shared by others, or there may be disagreement
about which vocabulary is best suited for a specific aspect of research. As a result, it can …